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BioWorld - Wednesday, July 29, 2026
Home » SARS-CoV-2

Articles Tagged with ''SARS-CoV-2''

Infection

Merck Sharp & Dohme synthesizes 3CLpro inhibitors for COVID-19

Aug. 6, 2024
Merck Sharp & Dohme LLC has disclosed 3C-like proteinase (3CLpro; Mpro; nsp5) (SARS-CoV-2; COVID-19 virus) inhibitors reported to be useful for the treatment of SARS-CoV-2 infection (COVID-19).
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Mark Mitchnick, CEO, Red Queen
Infection

Red Queen targets infections with predatory lipopeptides

Aug. 6, 2024
By Karen Carey
Armed with $55 million in series A funds and a U.S. government contract, Cambridge, Mass.-based Red Queen Therapeutics Inc. launched operations this week, with plans to advance its novel stapled lipopeptide platform, which creates new antiviral therapies that do not rely on the immune system to work.
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Infection

Enanta Pharmaceuticals describes new PL-pro inhibitors

July 22, 2024
Enanta Pharmaceuticals Inc. has patented compounds acting as nonstructural protein 3 (nsp3, PL-pro; SARS-CoV-2) inhibitors reported to be useful for the treatment of asthma, SARS-CoV-2 infection (COVID-19), rhinovirus, norovirus and lung infections.
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Fruit fly muscles showing how well mitochondria produce energy
Infection

Infection and brain neuroinflammation weaken muscles

July 19, 2024
By Mar de Miguel
Muscle fatigue associated with brain inflammation could be prevented by modulating certain cytokines. Researchers at Washington University in St. Louis (WUSTL) have studied inflammation in the CNS in infection models of Escherichia coli, SARS-CoV-2 and amyloid-β toxicity, unveiling its impact on motor function, the role of IL-6 in this process and how to mitigate it in chronic disease.
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Immune

Imidazopyrimidine TLR7/8 agonist adjuvant formulation with enhanced Th-polarizing immunity

July 17, 2024
Researchers from Children’s Hospital Boston and affiliated organizations have reported the discovery and preclinical characterization of a novel TLR7/8 agonist adjuvant for vaccination, PVP-037.
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Digital lungs illustration
Respiratory

The TOX-RAGE axis emerges as a potential target for severe pulmonary infections

July 16, 2024
Severe COVID-19 causes a complex lung injury implicating dysregulated immune responses, endothelial dysfunction and coagulopathy, consistent with acute respiratory distress syndrome (ARDS).
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Infection

Pfizer describes new PLpro inhibitors for SARS-CoV-2

July 3, 2024
Pfizer Inc. has identified nonstructural protein 3 (nsp3; PLpro) (SARS-CoV-2; COVID-19 virus) inhibitors reported to be useful for the treatment of SARS-CoV-2 (COVID-19) infection.
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Infection

Merck Sharp & Dohme discovers new 3CLpro inhibitors

June 21, 2024
Merck Sharp & Dohme LLC has described 3C-like proteinase (3CLpro; Mpro; nsp5) (SARS-CoV-2; COVID-19 virus) inhibitors reported to be useful for the treatment of Middle East respiratory syndrome coronavirus (MERS-CoV), SARS-CoV and SARS-CoV-2 infection (COVID-19).
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Infection

Enanta Pharmaceuticals presents new antivirals for SARS-CoV-2

June 14, 2024
Enanta Pharmaceuticals Inc. has divulged macrocyclic chalcone-amide compounds acting as non-structural protein 3 (nsp3; PL-pro) (SARS-CoV-2; COVID-19 virus) inhibitors.
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Roches Cobas system and test

Roche gains US EUA for SARS-CoV-2, influenza, RSV molecular test

June 12, 2024
By Shani Alexander
The granting of emergency use authorization by the U.S. FDA to Roche AG for its four-in-one molecular test for SARS-CoV-2, Influenza A/B viruses and respiratory syncytial virus will allow the company to quickly bring the test to near-patient care environments ahead of the flu season, to address a real need in the marketplace, Ian Parfrement, head of the point of care customer area, at Roche Diagnostics, told BioWorld.
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