Alzheimer’s disease can be divided into multiple subtypes based on gene expression patterns, investigators at the Mount Sinai School of Medicine reported in the Jan. 6, 2021, issue of Science Advances. The work, corresponding author Bin Zhang told BioWorld, is “the first major finding of subtypes in Alzheimer’s disease.”

BioWorld looks at translational medicine, including: Cellular underpinnings of allergen immunotherapy success.

BioWorld looks at translational medicine, including: New causal gene for chronic kidney disease; New classification scheme for glioblastomas.

BioWorld looks at translational medicine.

BioWorld looks at translational medicine.

BioWorld looks at translational medicine, including: CARs with switches.

Using an adenine base editor, researchers at the U.S. NIH, Vanderbilt University Medical Center and Harvard University have succeeded in treating the premature aging syndrome Hutchinson-Guilford progeria syndrome (progeria) in mice, extending the animals’ lifespan and preventing much of the vascular damage that is typically the cause of death in children with progeria.

BioWorld looks at translational medicine, including: ApoE multitasks for regulating brain lipids.

BioWorld looks at translational medicine, including: Liver metastases are immunosuppressive.

BioWorld looks at translational medicine.