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Home » Topics » Science, BioWorld MedTech

Science, BioWorld MedTech
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DNA illustration

Sarepta and Genedit report early success in polymer nanoparticle delivery for neuromuscular disorders

Feb. 4, 2022
By Annette Boyle
Combining Sarepta Therapeutics Inc.’s gene editing technology and Genedit Inc.’s Nanogalaxy platform to treat neuromuscular disorders shows promising potential, the companies reported. A year into the research collaboration, Genedit’s polymer nanoparticles have demonstrated the ability to deliver therapeutic cargo to specific muscle tissue following system administration of targeted genetic medicines.
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Nanotech illustration

Researchers are testing a new generation of implantable nanodevices used in myocardial infarction

Feb. 4, 2022
By Bernard Banga
PARIS – An interdisciplinary academic research consortium in Italy has devised and tested nanowires that restore physiological cell-to-cell conductance. This research team, led by the Experimental and Applied Medical Technology Lab (Tecmed Lab) at the Department of Medicine and Surgery at the University of Parma, Italy, has just published the results of multiple local in situ injections of nanowires into left ventricular infarct regions in Nature Communications.
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Elderly hands holding broken brain structure

South Korea’s GIST completes preclinical studies for noninvasive Alzheimer’s therapy

Jan. 28, 2022
By Gina Lee
South Korea’s Gwangju Institute of Science and Technology (GIST) has completed a preclinical study for a noninvasive therapy for Alzheimer’s disease. The "ultrasound-based gamma entrainment” technique involves syncing up gamma waves, or brain waves above 30 Hz, with an external oscillation of a given frequency. This happens naturally by exposing a subject to a repetitive stimulus, such as sound, light, or mechanical vibrations.
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Tape measure, apple on scale

Insulin is tissue-specific, with link to weight complex

Jan. 18, 2022
By Subhasree Nag
A study by researchers led by David James from the University of Sydney showcases the diversity in metabolic responses observed across different mouse strains exposed to two different diets that demonstrates the heritability of metabolic traits.
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Futuristic medicine research illustration with petri dishes and pipette

Machine learning approach speeds resistance identification

Jan. 14, 2022
By Anette Breindl
A team led by researchers from the ETH Zürich and the University of Basel has used a combination of mass spectrometry data and machine learning to predict antibiotic resistance of clinical bacterial samples. The results, which were published in the Jan. 10, 2022, issue of Nature Medicine, could speed the identification of optimal antibiotic regimens for patients.
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Streptococcus pneumoniae in lungs

Researchers restore front-line antibiotics' effects

Jan. 13, 2022
By Tamra Sami
Researchers at the Peter Doherty Institute for Infection and Immunity, the University of Queensland, Griffith University, the University of Adelaide and St. Jude Children's Research Hospital have unlocked a key to making existing front-line antibiotics work again against Streptococcus pneumoniae, the bacteria that cause pneumonia.
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Pig heart transplant
Of pigs and people

Xenotransplanted heart clears first (and lowest) hurdle

Jan. 11, 2022
By Anette Breindl
Clinicians at the University of Maryland have transplanted a heart from a genetically modified pig bred by Revivicor Inc., a subsidiary of United Therapeutics Corp., into a patient with end-stage heart failure.
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Emulate Brain-Chip

Emulate’s Brain-Chip seeks clues to gravity’s effect on the brain

Jan. 7, 2022
By Meg Bryant
Space travel has known effects on human health and biology. Some, such as loss of bone density, are well understood, while others, like inflammation, are not. Now, organ-on-a-chip maker Emulate Inc. is conducting experiments on the International Space Station U.S. National Laboratory (ISS-NL) aimed at revealing clues to how the brain functions in microgravity.
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pop-up sensor nanotech

3D ‘pop-up’ sensors measure cardiac signals inside a single heart cell

Jan. 7, 2022
By David Godkin
University of California San Diego engineers have developed tiny 2D sensors that pop up to become a 3D assemblage of microscopic sensors for directly measuring the movement and speed of electrical signals inside the heart. According to nanoengineering professor Sheng Xu, the nanotechnology has enormous implications for heart doctors anxious to better diagnose and treat arrhythmia, heart attack and other diseases.
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Glucose testing

The enzyme NOX4 is essential for the antidiabetes effect of exercise

Jan. 6, 2022
By Subhasree Nag
In a recent study, investigators led by Tony Tiganis at Monash University, Australia have identified that upregulation of the enzyme NOX4 (NADPH oxidase 4) boosted levels of reactive oxygen species and protected development of insulin resistance in both aged as well as obese mice.
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