BioWorld looks at translational medicine, including: Edited stem cells reverse mouse diabetes; Noncoding TET2 variants affect neurodegeneration risk; Pancreatic cancer uses autophagy to hide from immune system; Heart failure hormone has role in sepsis; NRF2 wakes sleeping tumor cells; Oral drug can wake up telomerase; Cheating cell death improves infarct outcomes; Older siblings’ example turns stem cells into heart cells; Lung changes from PD drug hopeful are reversible; Platelets play role in Tylenol toxicity.
Keeping you up to date on recent developments in diagnostics, including: Automated CT biomarkers predict future CV events; PCR heightens detection of scabies; High BMI linked to dementia via complement component.
By analyzing the antibody response of a survivor of Marburg virus infection, researchers at the University of Texas Medical Branch and Vanderbilt University Medical Center have gained new insights into the function of non-neutralizing antibodies in fighting infections.
Keeping you up to date on recent developments in orthopedics, including: Co-delivery of IL-10 and NT-3 to enhance spinal cord injury repair; Marshall School of Medicine team explores surgery technology resulting in fewer incisions; Researchers discover treatment for spasticity in mice, following spinal cord injuries.
Keeping you up to date on recent developments in oncology, including: Targeted Interleukin-12 heats up cold tumors; Therapy allows immune system to ‘manganese’ up against cancer; Proton therapy less toxic than IMRT in new study; Technetium supplies struggling under distribution headaches.
Keeping you up to date on recent developments in cardiology, including: Modeling the post-infarct heart; Researchers: Cancer immunotherapy poses threat to heart muscle; Lighting up the path for heart procedures.
The largest study to date on hypermutated gliomas has delivered new insights into their origin, as well as their response to several different treatments. Specifically, even though they are hypermutated, such tumors are unlikely to respond to PD-1 blockers.
Keeping you up to date on recent developments in neurology, including: Gene variant may protect against Alzheimer's; Miniature microscope used to study neural circuit activity in nonhuman primate model; Dopamine has epigenetic role in addiction; Depression’s structural problem.
Chinese scientists have shown for the first time that the down-regulation of a single RNA-binding protein, polypyrimidine tract-binding protein 1 (Ptbp1), locally converted glial cells to neurons and showed promise for treating the symptoms of neurodegenerative diseases in mice.
BioWorld looks at translational medicine, including: Engineering better bacterial backstabbers; Targeting bystander protein improves sepsis outcome; Long noncoding RNA has sex-specific role in depression; Targeted IL-12 heats up cold tumors; Fast route from fibroblasts to photoreceptors; Eating pro-inflammatory IgG helps prevent liver failure; Depression’s structural problem; Modeling the post-infarct heart; Interleukins rile each other up in reaction to implants; Complement links high BMI to dementia.
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