BioWorld looks at translational medicine, including: See in 3D; Tolerizing DCs are made, not born; GOF, LOF mutations take different paths to same result; NEFA’s nefarious role in pancreatitis; Comprehensive look identifies insulin autoantigens.
Keeping you up to date on recent developments in diagnostics, including: Preventing birth defects; Full-waveform inversion for brain imaging; From junk to noncoding to coding; An efficient strategy for Legionella detection.
Like Berlin patient Timothy Ray Brown before him, London patient Adam Castillejo, whose case was top story of the 2019 Conference on Retroviruses and Opportunistic Infections (CROI), energized the HIV cure research field by his sheer existence. Curing HIV, Pablo Tebas told the audience at a themed discussion on curative strategies, “has been considered [for] a long time the holy grail.”
CYBERSPACE – Continuing improvements in HIV treatment and progress toward a cure notwithstanding, an effective vaccine will be necessary to gain the upper hand in the decades-long fight against the pandemic.
Keeping you up to date on recent developments in orthopedics, including: Artificial intelligence can scan doctors' notes to distinguish between types of back pain; Researchers discover new stem cells that can generate new bone; Study shows improved outcomes for patients with Arthrosurface Ovo arthroplasty system.
Keeping you up to date on recent developments in oncology, including: Cost effectiveness of biomarker testing for lung cancer screening eligibility still iffy; Unexpected mechanism, combination possibilities for CDK 4/6 inhibitors; Protons pushing into Peoria; BWXT on the move in Tc-99 production.
Keeping you up to date on recent developments in cardiology, including: Scientists see connection between low blood pressure, high mortality in older adults; New genetic variants discovered that cause heart disease in infants; Using PET imaging in post-transplant care for heart patients.
Keeping you up to date on recent developments in neurology, including: Seismic imaging technology could deliver finely detailed images of the human brain; Scientists monitor brains replaying memories in real time; Drug shows promise in reducing deadly brain swelling after stroke.
In the Marvel Comic Universe, Venom is a superhero who started life as a supervillain and Spiderman foe. In the biopharma universe, scorpion venom is undergoing the same fate transformation, as separate papers this week reported new ways to use scorpion venom in two major therapeutic targeting challenges.
BioWorld looks at translational medicine, including: Serine improves memory in Alzheimer’s mouse model; From junk to noncoding to coding; Keeping stem cells quiescent enables greater ultimate potency; Female, male fat tissue flight inflammation differently; BioPROTACs cut out middleman, and small molecule; ‘Gut bug’ has intratumoral effects; Decoy exosomes fight bacterial toxin; Unexpected mechanism, combination possibilities for CDK 4/6 inhibitors; In SIV infection, gut integrity is retained, not repaired.
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