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BioWorld - Thursday, August 11, 2022
Home » Topics » Artificial intelligence, BioWorld

Artificial intelligence, BioWorld
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3D model of a protein molecule

‘3D view of the protein universe’ as Deepmind reveals 200M protein structures

July 29, 2022
By Nuala Moran
No Comments
It is now possible to look up the 3D structure of every known protein following the latest release of Alphafold, an open database run in partnership by Deepmind, the London-based artificial intelligence company owned by Google parent Alphabet and the European Molecular Biology Laboratory’s European Bioinformatics Institute in Cambridge, U.K.
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Brain as light bulb filament

Thaler comes up short in district court fight over inventorship rights for AI

Sep. 7, 2021
By Mark McCarty
No Comments
The question of whether an artificial intelligence (AI) algorithm can be an inventor has been making the rounds in the past couple of years, and the question came up again in the U.S. District Court for the Eastern District of Virginia. Stephen Thaler, who developed the Device for the Autonomous Bootstrapping of Unified Sentience (DABUS) algorithm that has been credited with two inventions, failed to persuade the court that an algorithm qualifies as an “individual,” and thus patents must still be assigned to humans, at least where the U.S. Patent and Trademark Office is concerned.
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AI microchip illustration

WHO paper on AI lacking in specifics regarding transparency

July 1, 2021
By Mark McCarty
No Comments
The World Health Organization’s (WHO) guidance for ethics and governance for artificial intelligence (AI) in health discusses several issues regarding regulation, including the question of transparency for the algorithm’s source code. The WHO paper is not prescriptive on this and several other issues, however, raising the prospect that regulatory entities will not be discouraged from adopting policies that run afoul of intellectual property concerns and thus impede advances in AI.
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Silhouette with AI illustration

Having to explain itself makes for better AI decisions

June 11, 2021
By Anette Breindl
No Comments
Researchers at the University of Washington reported in the May 31, 2021, issue of Nature Medicine that artificial intelligence (AI) algorithms meant to recognize COVID-19 infections based on chest X-rays picked up on confounders, selecting “shortcuts” such as patient age or positioning in the X-ray as a basis for their predictions.
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Aman Kant, chief business officer, Inveniai

Shionogi bags agreement for Inveniai’s AI drug discovery platform Alphameld

April 29, 2021
By Gina Lee
No Comments
HONG KONG – Shionogi & Co. Ltd. has inked a multitarget drug discovery collaboration for Inveniai LLC’s artificial intelligence and machine learning platform Alphameld. Inveniai is eligible to receive up to $200 million per program through a combination of up-front payments, development and commercial milestones, and royalties.
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Head filled with digital data

Using AI/ML to reduce the costs and risks of CNS diseases research

March 10, 2021
By Peter Winter
No Comments
With the prevalence of central nervous system disorders such as Alzheimer’s disease, multiple sclerosis, epilepsy, Parkinson’s disease and stroke increasing annually, the need for novel therapeutics to treat neurologic and psychiatric disorders has never been greater. Unfortunately, even though there is a significant unmet medical need, because of the high risk and low approval rates of drugs targeting those devastating diseases, in the past decade big pharma companies have been dramatically reducing their R&D spending on CNS disorders, noted Naheed Kurji, president and CEO of Toronto-based Cyclica Inc.
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Exscientia building out AI-derived pipeline with $40M series C extension

March 5, 2021
By Nuala Moran
No Comments
LONDON – Artificial intelligence (AI) drug design specialist Exscientia Ltd. has completed a sizable extension to its series C, adding a further $40 million to the $60 million raised in May 2020.
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Health professional touching screen, digital/medical icons

Hummingbird taps Tempus’ AI for clinical trial in rare NRG1 fusion patients

Dec. 17, 2020
By David Ho
No Comments
HONG KONG – Hummingbird Bioscience Pte. Ltd. is collaborating with artificial intelligence (AI) company Tempus Labs Inc. to advance HMBD-001, a differentiated anti-HER3 neutralizing antibody developed using Hummingbird's Rational Antibody Discovery platform, into clinical trials in HER3-driven cancers, including those that harbor neuregulin 1 (NRG1) fusions.
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Evan Feinberg, CEO and co-founder, Genesis

Near its beginning, Genesis brings in a $52M series A

Dec. 2, 2020
By Lee Landenberger
No Comments
Genesis Therapeutics Inc. CEO and co-founder Evan Feinberg likens the collaboration of his company’s team of chemists, biologists and software developers to that of a jazz band. Everyone has to be familiar with everyone else’s roles and responsibilities in order to do their job, or play a solo, when it’s their turn.
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Gastrointestinal-microbiome

AI microbiome firm Xbiome raises $20M+ to push candidates into clinic

Dec. 1, 2020
By Elise Mak
No Comments
Shenzhen Xbiome Biotech Co. Ltd., an artificial intelligence (AI)-based microbiome drugmaker, raised more than $20 million in a series B+ round, Xbiome CEO Yan Tan told BioWorld, financing that will help the company launch its phase I trial next year. It has been a year since the drugmaker closed a $14 million series B round. During this period, Tan said Xbiome submitted an IND to the FDA in October for its fecal microbiota transplant (FMT) capsule candidate, a potential treatment for graft-vs.-host disease.
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