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BioWorld - Wednesday, May 31, 2023
Home » Topics » Clinical, BioWorld MedTech

Clinical, BioWorld MedTech
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Study shows Exact benefit of early cancer diagnosis

May 26, 2023
By Annette Boyle
No Comments
Exact Sciences Corp.’s long-term analysis of results from the Detecting cancers Earlier Through Elective mutation-based blood Collection and Testing (DETECT-A) study found that all patients diagnosed and treated for stage I or II cancers identified through its blood-based multi-cancer early detection (MCED) test remained cancer-free more than four years after diagnosis. Half of all the participants with cancer detected remained alive at four years, notable because most of the detected cancers had no recommended screening tests or standards. The results will be presented at the American Society of Clinical Oncology meeting June 2-6.
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EuroPCR 2023

Renal denervation, the comeback kid

May 26, 2023
By Shani Alexander
No Comments
Renal denervation (RDN) was described as the “comeback kid” at the recent EuroPCR conference in Paris where participants argued that following the success seen in several sham-controlled trials, there is now no doubt about the safety and the efficacy of the technology as a treatment for hypertension. The device-based procedure should now be used as a therapy option to reduce high blood pressure in patients, delegates heard.
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Clinical trial virtual display

UK investing £121M to revive clinical trial activity as part of overall life sciences boost

May 26, 2023
By Nuala Moran
No Comments
The U.K. government has announced £121 million (US$148 million) in funding to reboot the commercial clinical trials system after a sharp decline saw the number of industry-sponsored studies falling by 44% from 2017 to 2021.
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antigraft.jpg

Reddress lands $26M for autologous wound management system

May 25, 2023
By Meg Bryant
No Comments
Reddress Ltd. secured $26 million in a series D financing aimed at further advancing its autologous, point-of-care wound management solution. The funds will be used to grow uptake of its Actigraft product suite, pursue global partnerships and expand its blood-based technology to treat more conditions.
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Magnus Medical’s Saint system alters brain signals in patients with severe depression

May 23, 2023
By Meg Bryant
No Comments
Results from a new study suggest that treatment with Magnus Medical Inc.'s Saint neuromodulation system causes abnormal brain signals to become normal by reversing the direction brain signals flow in severely depressed individuals. The researchers also identified a new biomarker that could help doctors diagnose and treat major depressive disorder (MDD).
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Polymer illustration
Heart Rhythm 2023

‘Earring’ the call for a non-invasive solution to postural orthostatic tachycardia

May 23, 2023
By Mark McCarty
No Comments
Jewelry used to adorn the human ear is not the stuff of legend where medical technology is concerned, but a clip-type device, similar to an earring, that can be worn on the tragus of the ear might soon become daily wear for those who suffer from postural orthostatic tachycardia syndrome (POTS). Researchers at the University of Oklahoma say their self-administered clip can relieve POTS with just one hour’s use per day over a period of two months, a finding that might prove an inexpensive and convenient treatment for as many as one million Americans who currently have few treatment options.
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Heart Rhythm 2023

Ebr’s WiSE device promises solution to left bundle branch pacing dilemma

May 23, 2023
By Mark McCarty
No Comments
Bringing both ventricles back into synchrony has long been the subject of cardiological hopes in patients with heart failure, but current approaches to maximizing the function of the left ventricle leave many patients in a desperate state of cardiac dyssynchrony. However, Ebr Systems Inc., has reported the results of a study that demonstrates that its WiSE device can pace the left ventricle in patients who are unresponsive to conventional pacing in an effort to restore optimal left ventricular function, a development Sunnyvale, Calif.-based Ebr says will allow the company to conclude a premarket filing with the U.S. FDA.
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UCSFDBS2.jpg

Where does it hurt? For chronic pain, in the orbitofrontal cortex

May 22, 2023
By Anette Breindl
No Comments
Long-term brain recordings from four patients with chronic pain have led investigators at the University of California at San Francisco to identify brain signals that could serve as biomarkers for each individual patients’ pain.
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Clinical research concept with medical icons on light bulb
Heart Rhythm 2023

Pulsed field ablation gains yet more traction in new studies

May 22, 2023
By Mark McCarty
No Comments
Pulsed field ablation (PFA) seems to have seized the moment in the field of cardiac electrophysiology, given its seemingly superior performance over other ablation modalities as a treatment for atrial fibrillation (AF). New data from three studies were presented at this year’s annual meeting of the Heart Rhythm Society that further confirm the value of PFA as a treatment for both persistent and paroxysmal AF with data sets that seem to confirm that PFA is poised to sweep aside the current standards for ablation, potentially overturning a treatment paradigm that took decades to establish.
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Heart Rhythm 2023

New AI software accurately depicts patients at risk of sudden cardiac death

May 22, 2023
By Mark McCarty
No Comments
Recent developments may seem to have rendered artificial intelligence (AI) little more than the latest internet sensation, but a presentation at this year’s annual meeting of the Heart Rhythm Society confirms yet again that AI is much more than just a trend. A new AI algorithm paired with a single-lead electrocardiogram accurately predicted the onset of ventricular tachycardia in 88% of patients in an outcome that could enable cardiologists to thwart thousands of sudden cardiac death (SCD) events each year, potentially ushering in a new age of cardiac care across the globe.
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