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BioWorld - Sunday, February 15, 2026
Home » Topics » Clinical

Clinical
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Seikagaku, Ono Pharma plan next steps for arthritis drug after positive Japan phase III results

June 16, 2020
By Gina Lee
HONG KONG – Japan’s Seikagaku Corp. is contemplating the next move for its ONO-5704/SI-613 (diclofenac etalhyaluronate), a treatment for arthritis that it is co-developing with fellow Japanese company Ono Pharmaceutical Co. Ltd.
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Sleep cartoon
Sleepless in Cambridge

Sleep deprivation kills through punch to the gut

June 16, 2020
By Anette Breindl
The disconnect between the need for sleep and the possession of a brain is what prompted Dragana Rogulja, an assistant professor of neurobiology in the Blavatnik Institute at Harvard Medical School, and her team to take a look at multiple tissues in sleep-deprived flies and mice.
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Coronavirus, lungs

Dexamethasone shows benefit in treating COVID-19 in Recovery trial

June 16, 2020
By Nuala Moran
LONDON – In the first major breakthrough in therapeutics for COVID-19 infection, dexamethasone has been shown to have a statistically significant impact on mortality in the most seriously ill patients.
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In the clinic for June 16, 2020

June 16, 2020
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Addex, Amarin, Anavex, Arecor, Bionic Sight, Dermavant, Enb, Exicure, Forma, Humanigen, Immunicum, Janssen, Merck, Neuren, Oncopeptides, PDS, Pfizer, Provention, Renibus, Sanofi, Sarepta, Vyome.
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Respiratory infection

Humanigen says small lenzilumab study shows benefit for COVID-19 patients

June 15, 2020
By Michael Fitzhugh
Shares of Humanigen Inc. (NASDAQ:HGEN) climbed 30.2% to $5.31 on Monday after the company disclosed that, when treated with the company's anti-GM-CSF antibody, lenzilumab, 12 hospitalized patients with severe or critical pneumonia as a result of COVID-19 showed "rapid clinical improvement."
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No sweat: Brickell’s anticholinergic data paves the way to Asia

June 15, 2020
By Lee Landenberger
All the primary and secondary efficacy endpoints were met in Boulder, Colo.-based Brickell Biotech Inc.’s pivotal phase III study of the anticholinergic sofpironium bromide in treating primary axillary hyperhidrosis, which involves excessive sweating in the armpits that interferes with daily life and work.
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Coronavac product packaging

Sinovac unveils positive results for COVID-19 vaccine candidate, aims to start phase III next month

June 15, 2020
By Elise Mak
BEIJING – Nasdaq-listed Chinese vaccine developer Sinovac Biotech Ltd., of Beijing, said the preliminary results of the phase I/II trials of its COVID-19 inactivated vaccine candidate, Coronavac, demonstrated favorable immunogenicity and safety profiles.
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COVID-19 vaccine vials

Astrazeneca to give 400M COVID-19 vaccine doses to Europe; data expected August/September

June 15, 2020
By Nuala Moran
LONDON - The EU has secured a supply of the most advanced COVID-19 vaccine in development, in a deal with Astrazeneca plc for up to 400 million doses of AZD-1222, with deliveries starting by the end of 2020.
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Creatv blood test predicts response to lung cancer treatment

June 12, 2020
By Annette Boyle
Creatv Microtech Inc. has developed a simple blood test that can predict response to chemoradiation and consolidated immunotherapy in patients with non-small-cell lung cancer (NSCLC).
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Singapore’s Tychan kicks off speedy phase I trial for COVID-19 monoclonal antibody

June 12, 2020
By David Ho
HONG KONG – Singapore-based Tychan Pte. Ltd. is starting a phase I trial for a novel monoclonal antibody (MAb) that specifically targets SARS-CoV-2, the coronavirus that causes COVID-19. The trial is expected to take only around six weeks to complete.
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