The activity of many proteins is controlled through phosphorylation by kinases and dephosphorylation by phosphatases. Overactive kinases are one of the major drivers of tumors and, as a result, kinase inhibitors are a mainstay of oncology drug development. But “activation of the brakes, the phosphatases, could be equally therapeutically viable for the treatment of a broad range of cancers” to kinase inhibition, Goutham Narla told the audience at the 2020 American Association for Cancer Research (AACR) meeting.
CYBERSPACE – At a series of new drugs on the horizon sessions at the 2020 American Association for Cancer Research (AACR) Virtual Annual Meeting I, a variety of companies presented preclinical and clinical data for promising early stage oncology products.
DUBLIN – Thrive Earlier Detection Corp. and its academic and clinical collaborators have provided a first glimpse at the utility of a liquid biopsy test as a screening tool for picking up cancers in an asymptomatic population. In an interim one-year readout of data from the prospective five-year DETECT-A study in 10,000 women, an early version of Thrive’s Cancerseek test picked up 26 cancers ahead of standard-of-care screening, while the latter modality picked up another 24 cancers that Cancerseek missed.
New and updated preclinical and clinical data presented by biopharma firms at the American Association for Cancer Research’s Virtual Annual Meeting, including: Karus, Noxxon, Oric, Syndax, Tarveda, Trovagene.
New and updated preclinical and clinical data presented by biopharma firms at the American Association for Cancer Research’s Virtual Annual Meeting, including: Alligator, Alpine Immune, Aptose, Astrazeneca, Compugen, Iteos, Macrogenics, Merck, Rgenix, Ribon, Sutro, Theratechnologies, Vaccinex, Verastem.
New and updated preclinical and clinical data presented by biopharma firms at the American College of Cardiology’s 69th Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC Virtual), including: Amarin, Mesoblast, Resverlogix.
New and updated preclinical and clinical data presented by biopharma firms at the American College of Cardiology’s 69th Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC Virtual), including: Astrazeneca, Cytokinetics, Esperion, Janssen, Kiniksa, Merck, Mesoblast, Novartis, Regeneron.
The five-day Bio-Europe Spring 2020 conference, possibly the first ever life sciences partnering event staged in an all-virtual format, ended on Friday, March 27, with high hopes that the industry would return to face-to-face interactions next year in Barcelona.
Biopharma industry leaders in China who were the first to experience the chaos of the COVID-19 pandemic shared their thoughts during a closing plenary session of the virtual Bio-Europe Spring 2020 meeting.
At the beginning of this week, the digitally-delivered Bio-Europe Spring 2020 conference launched with 6,000 partnering meetings, 45 company presentations, more than 50 virtual exhibits and 12 panel discussions scheduled.
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