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Home » Topics » Disease categories and therapies

Disease categories and therapies
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US flag, Department of Health and Human Services flags

Opportunities for IVD, vaccine makers in US vector-borne disease plan

Feb. 7, 2024
By Mark McCarty
The U.S. Department of Health and Human Services (HHS) has released a sweeping plan that is designed to help manage vector-borne pathogens, such as the Zika virus, with the ultimate goal of reducing the related disease burden to zero.
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DNA sequence and COVID-19 virus cells

Genotyping technology can detect COVID variants quicker

Jan. 22, 2024
By Shani Alexander
Genotype assay testing can detect new variants of the COVID-19 virus six days faster than whole genome sequencing (WGS), with results returned in just three days — compared to nine for WGS — according to a study published in the Lancet Microbe.
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ubidx
Patents

UW spinout Ubidx Inc. develops home test for infectious diseases

Jan. 2, 2024
By Simon Kerton
Ubidx Inc. has designed a diagnostic system comprised of a fluidic single-use disposable and a base. While the fluidic single-use disposable or cartridge is generally described as being suitable for testing a single sample, the base or hub may be used numerous times to perform numerous tests using numerous fluidic single-use disposables or cartridges.
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US FDA’s updated guidance for susceptibility tests incorporates change control plans

Oct. 6, 2023
By Mark McCarty
The FDA’s draft guidance for predetermined change control plans (PCCPs) is just that, a draft guidance, but that has not stopped the agency from incorporating the underlying concepts into existing guidances. An example of this is the September 2023 guidance for antimicrobial susceptibility test (AST) system for breakpoints in device labeling, a document that represents a jarring update to the legacy version published in 2009.


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Setpoint resets gut response with VNS in Crohn’s disease

Oct. 3, 2023
By Annette Boyle
Neuroimmune modulation using vagus nerve stimulation (VNS) reduced Crohn’s disease symptoms and improved patient quality of life, a study published in the Journal of Crohn’s and Colitis found. The research by Setpoint Medical Corp. could provide a better option for patients with the autoimmune disorder than biologics, which often fail to work over time and can cause significant adverse effects.
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Liver and DNA

Hansoh and Olix ink $450M+ liver-focused siRNA therapeutics deal for greater China

Oct. 19, 2021
By Gina Lee and Doris Yu
In a deal that could be worth more than $450 million, Olix Pharmaceuticals Inc. and Hansoh Pharmaceutical Group Co. Ltd. have agreed to discover, develop, and commercialize siRNA therapeutics for various liver-based targets implicated in cardiovascular, metabolic, and other indications.
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Liver and DNA

Hansoh and Olix ink $450M+ liver-focused siRNA therapeutics deal for greater China

Oct. 13, 2021
By Gina Lee and Doris Yu
In a deal that could be worth more than $450 million, Olix Pharmaceuticals Inc. and Hansoh Pharmaceutical Group Co. Ltd. have agreed to discover, develop, and commercialize siRNA therapeutics for various liver-based targets implicated in cardiovascular, metabolic, and other indications.
Read More
Baby-Infant.png

Single-cell resolution reveals cell type, targets for neuroblastoma

Feb. 8, 2021
By Nuala Moran

The largest single cell transcriptomics study of neuroblastoma to date has discovered that this childhood cancer arises from a single type of embryonic cell, the sympathoblast. 


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Gene therapy offers potential but poses logistical challenges

Oct. 14, 2019
By Brian Orelli
The mantra for a while has been that it's not good enough to get your drug approved, you've got to get it payed for, too. For gene therapy treatments, the payment is more complex, and you can add manufacturing and supply chain logistics to the list of challenges.
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Three late-stage drugs look to battle in Cushing's syndrome market

Sep. 30, 2019
By Brian Orelli
The Cushing's syndrome market is heating up with three second-generation drugs in late-stage development to join the two approved medications, Signifor (pasireotide, Recordati SpA) and Korlym (mifepristone, Corcept Therapeutics Inc.), as well as a couple of off-label options.
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