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BioWorld - Sunday, July 5, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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Applied Pharmaceutical Science identifies new RET inhibitors

March 3, 2021

First-in-human data presented for SCC-244 in NSCLC

March 3, 2021

AbbVie initiates first-in-human study of ABBV-637 as monotherapy or in combination

March 3, 2021

Kazia out-licenses ovarian cancer drug to Oasmia to focus on glioblastoma

March 2, 2021
By Tamra Sami
PERTH, Australia – Sydney-based Kazia Therapeutics Ltd. has out-licensed its ovarian cancer drug, Cantrixil (TRX-E-002-1), to Sweden’s Oasmia Pharmaceutical AB in a deal worth up to $46 million. Oasmia will pay $4 million up front, and development milestones worth up to $42 million and double-digit sales royalties.
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Curocell scientist
Newco news

Curocell adds first South Korean IND approval for CAR T to its cart

March 2, 2021
By Gina Lee
HONG KONG – Daejeon, South Korea-based Curocell Inc. has received the first IND approval for a CAR T therapy in South Korea from the Ministry of Food and Drug Safety (MFDS).
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Cancer cell and DNA

Bacterial protease takes on ‘undruggable’ oncoprotein

March 2, 2021
By Anette Breindl
Scientists, despite their best efforts, have not been able to identify a way to inhibit the oncoprotein Myc. Uropathogenic Escherichia coli, though, has apparently figured it out. In the Feb. 11, 2021, online issue of Nature Biotechnology, researchers reported that an UPEC-produced protease depleted cellular Myc and improved survival in mouse models of bladder and colon cancer.
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Deal illustration

Agilent snags Resolution Bioscience in deal valued up to $695M

March 2, 2021
By Annette Boyle
Agilent Technologies Inc. will acquire Resolution Bioscience Inc. for $550 million in cash at closing and up to an additional $145 million based on performance milestones. The deal will expand Agilent’s cancer diagnostics offerings and its presence in next-generation sequencing (NGS) technology for the fast-growing precision medicine market. The acquisition is expected to close in April 2021.
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Carna receives CTA clearance for phase I study of BTK inhibitor AS-1763

March 2, 2021

FDA issues complete response letter for oral paclitaxel plus encequidar in metastatic breast cancer

March 2, 2021

Myoferlin inhibitor YQ-456 shows efficacy in PDX model of colorectal cancer

March 2, 2021
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