Liquid biopsy startup Delfi Diagnostics Inc. scooped up $100 million in a series A round led by Orbimed Advisors LLC. The company will use the funds to grow its team of cancer researchers and machine learning experts and to validate its next-generation blood-based testing technology in prospective clinical trials. Existing investors Menlo Ventures, Samsara Biocapital, Illumina Ventures, Av8 Ventures also participated in the round, along with new investors Foresite Capital, Northpond Ventures, Cowen Healthcare Investments and Rock Springs Capital.

Nantkwest Inc. and privately held Immunitybio Inc. trotted out positive early interim results from their advanced metastatic pancreatic cancer studies showing median survival rates more than double the historic rates: eight month’s survival compared to only three. “Anything beyond three months has an impact,” Patrick Soon-Shiong, Immunitybio’s CEO and Nantkwest’s executive chairman, told BioWorld, with understatement about one of the toughest to manage indications in medicine.

Investigators at Edinburgh University have discovered that the stem cell transcription factor SALL4 can recognize and bind to short AT-rich motifs across the genome and downregulate genes that are present in AT rich regions.

Newly launched Inzen Therapeutics Inc. is wrestling with cell loss and what information those cells impart as they die. The premise, that cells leave a legacy to living cells, is at the heart of the company as it works to find and develop therapies based on its Thanokine Biology, which the company said could be used for preventing and treating cancer, fibrotic disorders, immune-inflammatory disorders, metabolic disorders and degenerative diseases.