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BioWorld - Wednesday, February 11, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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Brain tumor illustration
Immuno-oncology

IL-24S/IL-15 fusion ‘superkine’ induces apoptosis of GBM cells, promotes antitumor immunity

July 4, 2025
No Comments
A recent study published in the Journal for Immunotherapy of Cancer has revealed a promising new approach for the treatment of glioblastoma (GBM), an aggressive and incurable form of primary brain cancer.
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Lunit

Lunit, Microsoft to codevelop cloud-based clinical AI solutions

July 3, 2025
By Marian (YoonJee) Chu
Lunit Inc. reported a new collaboration with Microsoft Corp. July 2 to jointly develop medical AI programs accessible on Microsoft’s Azure cloud platform.
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Index insights

FDA nods and deals fail to lift cancer stocks Verastem, Nextcure, Iovance

July 3, 2025
By Amanda Lanier
No Comments
After falling 4.74% in the first quarter (Q1), the BioWorld Cancer Index (BCI) staged a strong recovery in Q2, ending the period up 12.78%. The broader markets followed a similar trajectory, with the Dow Jones Industrial Average rebounding from a 4.41% loss at the end of April to close Q2 with a 3.64% gain. The Nasdaq Biotechnology Index also improved, trimming its earlier 5.37% decline to finish June down just 1.92%.
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Woman receiving chemotherapy

Chemotherapy-induced mutations are not universal phenomenon

July 3, 2025
By Nuala Moran
No Comments
The first systematic whole genome sequencing study of how chemotherapy damages healthy tissues has shown that many, but not all, of these agents cause mutations and premature aging of normal blood cells.
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Zanza time trickle in ESMO hourglass: more Exelixis CRC data?

July 3, 2025
By Randy Osborne
No Comments
Exelixis Inc.’s positive phase III top-line data June 22 with zanzalintinib (zanza) in colorectal cancer had Wall Street speculating anew about the odds with the tyrosine kinase inhibitor in an important indication.
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Xray showing lung cancer on tablet

FDA approves Dizal’s sunvozertinib for metastatic non-small-cell lung cancer

July 3, 2025
By Tamra Sami
No Comments
Four days ahead of its July 7 PDUFA date, the U.S. FDA granted accelerated approval to Dizal (Jiangsu) Pharmaceutical Co. Ltd.’s sunvozertinib (DZD-9008), branded as Zegfrovy, for treating adults with locally advanced or metastatic non-small-cell lung cancer with epidermal growth factor receptor exon 20 insertion mutations following platinum-based chemotherapy.
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Cancer

Scientists in Spain discover new senolytic compounds

July 3, 2025
Researchers at Servizo Galego de Saude and Universidade de Santiago de Compostela have described senolytic compounds reported to be useful for the treatment of cancer, metabolic diseases, and neurological, dermatological, cardiovascular, eye, renal and inflammatory disorders.
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Cancer

Incurix describes new c-Myc inhibitors

July 3, 2025
Incurix Co. Ltd. has identified Myc proto-oncogene protein (c-Myc) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Merck KGaA divulges new YAP1/TEAD and TAZ/TEAD interaction inhibitors

July 3, 2025
Merck KGaA has synthesized transcriptional coactivator YAP1/transcriptional enhancer factor (TEAD) and/or TAZ/TEAD interaction inhibitors reported to be useful for the treatment of cancer.
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Concept art for "cancer cells destroyed by oncogenic virus"
Immuno-oncology

IL-12-expressing oncolytic virus shows promise for solid tumors

July 3, 2025
No Comments
A newly developed oncolytic virus, SKV-012, has demonstrated promising results in preclinical studies and a phase I clinical trial for the treatment of advanced solid tumors.
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