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BioWorld - Thursday, April 23, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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DNA sequencing

Passengers, noncoding genome affect how cancers play out

Feb. 28, 2020
By Anette Breindl
Beyond every binary is a more complex reality. And so it is with driver and passenger mutations. The separation of tumor mutations into drivers and passengers underpins much progress in the development of targeted therapies.
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S1PR1 is required for tumor vascular normalization, enhancing the efficiency of antitumor agents

Feb. 28, 2020

DNA-PKcs inhibitor increases the antitumor activity of localized DNA-damaging therapies

Feb. 28, 2020

Epizyme discloses new SETD2 inhibitors

Feb. 28, 2020

Inflazome divulges new NLRP3 inflammasome inhibitors

Feb. 28, 2020

Novel alphaVbetea6-targeted PDC shows promise in preclinical models of PDAC

Feb. 28, 2020

New dihydroquinoxalinone analogues targeting tubulin with promising preclinical antitumor action

Feb. 28, 2020
Newco news

Aivita Biomedical ahead of schedule on its phase II glioblastoma trial

Feb. 27, 2020
By Lee Landenberger
Aivita Biomedical Inc.’s CEO, Hans Keirstead, just finished up a $12.5 million fundraiser and he’s prepping for another $12.5 million in a second effort. In the two months since he started raising the money, he has hired four more people and plans to hire four more by year-end, bringing the company’s headcount to 36 employees.
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T cells

TIGIT-al camera snapshot shows cancer bids fill the frame

Feb. 27, 2020
By Randy Osborne
During a recent investor event related to early drug development, Basel, Switzerland-based Roche Holding AG touted research by the firm’s Genentech unit into the cancer target known as TIGIT, or T-cell immunoreceptor with Ig and ITIM domains, and the pharma giant is hardly alone in the sizzling space.
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MapKure initiates first-in-human study of BGB-3245 in advanced or refractory tumors

Feb. 27, 2020
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