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BioWorld - Thursday, January 29, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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Cancer

Scinnohub patents new RET inhibitors

Nov. 6, 2025
No Comments
Scinnohub Pharmaceutical Co. Ltd. has disclosed compounds reported to be useful for the treatment of cancer and inflammatory diseases.
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Cancer cell in the cross-hairs
Cancer

Acrivon Therapeutics reports preclinical data on ACR-2316

Nov. 6, 2025
No Comments
Acrivon Therapeutics Inc. has developed a new WEE1/PKMYT1 inhibitor, ACR-2316, to overcome the limitations observed with previous WEE1 and PKMYT1 inhibitors in the treatment of cancer.
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Cancer

Accutar presents development of PI3Kα degrader-antibody conjugates

Nov. 6, 2025
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Accutar Biotechnology Inc. recently presented preclinical data on AC-4847, a first-in-class PI3Kα-targeting degrader-antibody conjugate (DAC) designed for selective treatment of PI3Kα-driven cancers.
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3D rendering of an antibody drug conjugate
Immuno-oncology

CBB-120 shows potent TROP2 targeting with improved safety margin

Nov. 6, 2025
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Researchers at Crossbridge Bio Inc. have conducted preclinical evaluation of CBB-120, a novel TROP2-directed dual-payload ADC designed to combine TOP1i and ATR inhibitor (ATRi) mechanisms for enhanced therapeutic efficacy.
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Celltrion building and skyline

Celltrion signs $744M deal with Kaigene, $500M with Mustbio

Nov. 5, 2025
By Marian (YoonJee) Chu
No Comments
Celltrion Inc. scored a hat-trick of deals to license new antibody candidates, including a $744 million deal with Kaigene Inc. Nov. 3, and a near $500 million deal with Mustbio Co. Ltd. Oct. 31.
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Bispecific antibodies with heavy chain in green and pink, light chain in blue and yellow
Newco news

Neok Bio launches with $75M to develop bispecific ADCs

Nov. 5, 2025
By Brian Orelli
No Comments
Neok Bio Inc. was formed earlier this year and is already on schedule to file an IND in a few months for its two bispecific antibody-drug conjugates (ADCs) to treat various types of tumors.
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Haisheng Zhang, CEO, Signet
Newco news

Signet builds new model for gastric cancer drug discovery

Nov. 5, 2025
By Tamra Sami
No Comments
Signet Therapeutics founder Haisheng Zhang is betting on organoids and AI to outsmart diffuse gastric cancer and the limits of traditional “clean” drug design.
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Cancer

Hangzhou Baicreat Pharma-Tech describes new POLθ inhibitors

Nov. 5, 2025
Hangzhou Baicreat Pharma-Tech Co. Ltd. has identified DNA polymerase θ (POLθ) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Shanghai Apeiron Biotechnology patents new PRMT5 degradation inducers

Nov. 5, 2025
Shanghai Apeiron Biotechnology Co. Ltd. has disclosed proteolysis targeting chimeras (PROTACs) reported to be useful for the treatment of cancer.
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Cancer

Prelude signs option deal, prioritizes JAK2 and KAT6A programs

Nov. 5, 2025
No Comments
Prelude Therapeutics Inc. has outlined its plans to prioritize programs within its pipeline and announced an exclusive option agreement with Incyte Corp.
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