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BioWorld - Monday, March 9, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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Celltrion building and skyline

Celltrion signs $744M deal with Kaigene, $500M with Mustbio

Nov. 5, 2025
By Marian (YoonJee) Chu
No Comments
Celltrion Inc. scored a hat-trick of deals to license new antibody candidates, including a $744 million deal with Kaigene Inc. Nov. 3, and a near $500 million deal with Mustbio Co. Ltd. Oct. 31.
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Bispecific antibodies with heavy chain in green and pink, light chain in blue and yellow
Newco news

Neok Bio launches with $75M to develop bispecific ADCs

Nov. 5, 2025
By Brian Orelli
No Comments
Neok Bio Inc. was formed earlier this year and is already on schedule to file an IND in a few months for its two bispecific antibody-drug conjugates (ADCs) to treat various types of tumors.
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Haisheng Zhang, CEO, Signet
Newco news

Signet builds new model for gastric cancer drug discovery

Nov. 5, 2025
By Tamra Sami
No Comments
Signet Therapeutics founder Haisheng Zhang is betting on organoids and AI to outsmart diffuse gastric cancer and the limits of traditional “clean” drug design.
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Cancer

Hangzhou Baicreat Pharma-Tech describes new POLθ inhibitors

Nov. 5, 2025
Hangzhou Baicreat Pharma-Tech Co. Ltd. has identified DNA polymerase θ (POLθ) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Shanghai Apeiron Biotechnology patents new PRMT5 degradation inducers

Nov. 5, 2025
Shanghai Apeiron Biotechnology Co. Ltd. has disclosed proteolysis targeting chimeras (PROTACs) reported to be useful for the treatment of cancer.
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Cancer

Prelude signs option deal, prioritizes JAK2 and KAT6A programs

Nov. 5, 2025
No Comments
Prelude Therapeutics Inc. has outlined its plans to prioritize programs within its pipeline and announced an exclusive option agreement with Incyte Corp.
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3D illustration demonstrating antibody-drug conjugate.
Immuno-oncology

Bispecific antibody-drug conjugate Gensci-143 shows promise in solid tumors

Nov. 5, 2025
No Comments
Changchung Genescience Pharmaceutical Co. Ltd., reported effects of the bispecific antibody-drug conjugate (ADC) of Gensci-143, is in metastatic castration-resistant prostate cancer (mCRPC) and other solid tumors.
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Immuno-oncology

Glycan-targeting ADC shows preclinical activity against HER2-low gastric cancer

Nov. 5, 2025
No Comments
Advanced gastric cancer continues to pose a significant medical challenge because of the scarcity of effective treatments and the frequent development of resistance to available drugs.
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Cancer cells being destroyed by immunotherapy
Immuno-oncology

Leukogene’s LTI-214 designated orphan drug for AML

Nov. 5, 2025
No Comments
Leukogene Therapeutics Inc.’s lead product candidate LTI-214 (M2T-CD33) has been awarded orphan drug designation by the FDA for the treatment of acute myeloid leukemia (AML).
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Celltrion, Portrai in $87M R&D deal to discover new drug targets

Nov. 4, 2025
By Marian (YoonJee) Chu
No Comments
Celltrion Inc. announced Oct. 29 the signing of an $87.75 million joint drug R&D agreement with AI and spatial transcriptome-based biotech Portrai Inc.
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