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BioWorld - Tuesday, June 2, 2026
Home » Topics » Disease categories and therapies » Cardiovascular

Cardiovascular
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Red blood cells in an artery with cholesterol

Kalexo enters dyslipidemia fray with preclinical siRNA candidate

Sep. 23, 2025
By Marian (YoonJee) Chu
Mabwell Bioscience Co. Ltd. and Aditum Bio Management Co. LLC announced, in after-market hours Sept. 17, an agreement to forge a new company called Kalexo Bio Inc. and load the biotech with a preclinical dyslipidemia asset via a potential $1 billion global license deal.
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Pfizer headquarters

Pfizer bets big in obesity with $7.3B Metsera takeover

Sep. 22, 2025
By Randy Osborne
No Comments
Pfizer Inc. bounced back in a big way from a GLP-1 trip-up this spring by making known its plan to take over what Metsera Inc. CEO Whit Bernard has called the “scale-obsessed” obesity player that he steers. Pfizer has agreed to pay $47.50 each for all of Metsera’s outstanding shares.
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AI disease prediction illustration
Artificial intelligence

New AI model simultaneously predicts risk of getting 1,000 diseases

Sep. 19, 2025
By Nuala Moran
No Comments
A new generative AI model trained on UK Biobank data can simultaneously forecast the risks and timing of developing over 1,000 different diseases a decade into the future. The developers applied similar algorithmic concepts to those used to develop large language models like ChatGPT and Gemini to build the model, using medical records from 402,799 participants in UK Biobank.
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Imperative Care Symphony

Imperative's Symphony plays well for clot removal, still not first chair

Sep. 18, 2025
By Annette Boyle
A late-breaking study presented at the PERT Consortium 2025 Pulmonary Embolism Scientific Symposium in San Diego showed marked clot-burden reduction with no device-related serious adverse events for Imperative Care Inc.’s Symphony thrombectomy system, though other companies have a head start. Circulation: Cardiovascular Interventions simultaneously published the study in an article titled “A Prospective Multicenter IDE Study of the Next-Generation Precision Aspiration Thrombectomy System for Intermediate-Risk Pulmonary Embolism: The SYMPHONY-PE Trial.”
Read More
Red blood cells in an artery with cholesterol

Kalexo enters dyslipidemia fray with preclinical siRNA candidate

Sep. 18, 2025
By Marian (YoonJee) Chu
No Comments
Mabwell Bioscience Co. Ltd. and Aditum Bio Management Co. LLC announced, in after-market hours Sept. 17, an agreement to forge a new company called Kalexo Bio Inc. and load the biotech with a preclinical dyslipidemia asset via a potential $1 billion global license deal.
Read More
Hand holding lightbulb
Cardiovascular

Kalexo Bio launches to develop Mabwell’s 2MW7141

Sep. 18, 2025
No Comments
Mabwell (Shanghai) Bioscience Co. Ltd. and Aditum Bio Management Company LLC have announced the launch of Kalexo Bio, a new company formed in conjunction with an exclusive global license agreement to develop 2MW7141.
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Cardiovascular

Korean scientists patent new 5-HT2A receptor antagonists

Sep. 16, 2025
Scientists at Gwangju Institute of Science & Technology and JD Bioscience Inc. have disclosed 5-HT2A receptor antagonists reported to be useful for the treatment of cancer, hyperlipidemia, obesity, diabetes, arteriosclerosis, hepatic steatosis, fibrosis and hypertension.
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Eko Health AI stethescope

Eko’s AI-stethoscope more than doubles heart disease detection

Sep. 11, 2025
By Annette Boyle
In a real-world study, Eko Health Inc.’s AI-enabled digital stethoscope dramatically increased detection rates for atrial fibrillation, heart failure and valvular heart disease in primary care settings. Researchers from Imperial College London presented results from the study at the European Society of Cardiology in Madrid.
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Elutia Elopro drug eluting bioenvelope

Boston Sci acquires Elutia's bioenvelopes for $88M

Sep. 9, 2025
By Annette Boyle
Elutia Inc. agreed to sell its Elupro and Cangaroo bioenvelopes for implantable medical devices to Boston Scientific Corp. for $88 million in cash. Elutia will use the funds to further development of NXT-41x, an antibiotic biomatrix designed to reduce post-surgical complications in breast reconstruction.
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Digital heart illustration

Braveheart licenses Hengrui's heart drug HRS-1893 in $1B deal

Sep. 9, 2025
By Marian (YoonJee) Chu
No Comments
Braveheart Bio Inc. is paying $65 million up front to license Jiangsu Hengrui Pharmaceuticals Co. Ltd.’s oral hypertrophic cardiomyopathy drug candidate called HRS-1893.
Read More
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