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BioWorld - Thursday, December 18, 2025
Home » Topics » Disease categories and therapies » Cardiovascular

Cardiovascular
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Deal illustration
Jefferies London Healthcare Conference

Siemens partners with Boston Sci, eyes standalone growth

Nov. 19, 2025
By Shani Alexander
The recent strategic partnership Siemens Healthineers AG recently entered into with Boston Scientific Corp. to develop and commercialize an Acunav 4D intracardiac echocardiography catheter could drive “significant growth” for the company, Jochen Schmitz, CFO, at Siemens, told delegates at the Jefferies Global Healthcare Conference, in London.
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Emulate Chip R1 Brain

US, European biotechs lead budding organ-on-a-chip market

Nov. 19, 2025
By Marian (YoonJee) Chu
U.S. and European organ-on-a-chip specialty biotechnology companies are driving development of organ-on-a-chip technologies, fueled by the U.S. FDA’s decision to phase out animal testing for investigational new drugs.
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Medtronic - Symplicty Spyral HTN

Pulsed field ablation lifts Medtronic Q2 results

Nov. 18, 2025
By Annette Boyle
Medtronic plc posted solid fiscal year second-quarter results led by the cardiovascular business with 9.3% growth. The Affera Sphere-9 pulsed field ablation system tripled the company’s sales in the hot PFA segment and pushed the cardiac ablation solutions unit to 71% growth, a nice uptick from the nearly 50% seen in its Q1.
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Microbiome illustration
Dental

‘Most complete’ map of oral microbiome enables links to systemic disease

Nov. 18, 2025
By Marian (YoonJee) Chu
No Comments
South Korean researchers led by Lee In-suk of Yonsei University have reported the most complete oral microbiome catalog to date, with more than 72,000 genomes. Detailed in Cell Host & Microbe on Nov. 12, 2025, the database is expected to serve as a universal platform for academia and enable “precision microbiome medicine” for the industry, Lee told BioWorld.
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Deal handshake with coin, chart background

ABL Bio’s Grabody lands second $2.6B deal, this time with Lilly

Nov. 13, 2025
By Marian (YoonJee) Chu
No Comments
ABL Bio Inc. inked a license and research agreement with Eli Lilly and Co. worth up to $2.6 billion to develop multiple therapeutics using the Grabody-B platform. Under the terms announced Nov. 12, ABL will receive a $40 million up-front payment and up to $2.56 billion in development, regulatory and commercialization milestones, plus tiered royalties on net sales.
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Deal handshake with coin, chart background

ABL Bio’s Grabody lands second $2.6B deal, this time with Lilly

Nov. 13, 2025
By Marian (YoonJee) Chu
No Comments
ABL Bio Inc. inked a license and research agreement with Eli Lilly and Co. worth up to $2.6 billion to develop multiple therapeutics using the Grabody-B platform. Under the terms announced Nov. 12, ABL will receive a $40 million up-front payment and up to $2.56 billion in development, regulatory and commercialization milestones, plus tiered royalties on net sales.
Read More
Obesity and heart disease illustration
Endocrine/metabolic

35pharma’s HS-235 as new approach for obesity treatment

Nov. 13, 2025
No Comments
Researchers at 35pharma Inc. have recently presented data for the activin receptor inhibitor HS-235, which is under development for the treatment of obesity as it exerts body composition and metabolism control.
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Microbiome illustration
Dental

‘Most complete’ map of oral microbiome enables links to systemic disease

Nov. 13, 2025
By Marian (YoonJee) Chu
No Comments
South Korean researchers led by Lee In-suk of Yonsei University have reported the most complete oral microbiome catalog to date, with more than 72,000 genomes. Detailed in Cell Host & Microbe on Nov. 12, 2025, the database is expected to serve as a universal platform for academia and enable “precision microbiome medicine” for the industry, Lee told BioWorld.
Read More
Boston Scientific Corp.’s Watchman Flx device
AHA Scientific Sessions

CLOSURE-AF study not the end of the line for LAAC devices

Nov. 11, 2025
By Mark McCarty
At first glance, the results of the CLOSURE-AF study would seem to spell doom for left atrial appendage closure devices for patients at risk of stroke, but there is some noise in the signal, including that the devices used in the study no longer represent the state of the med-tech art.
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Cardiovascular

Monte Rosa’s MRT-8102 suppresses NLRP3 inflammasome activation

Nov. 11, 2025
No Comments
Researchers from Monte Rosa Therapeutics Inc. reported preclinical efficacy data on MRT-8102, a selective NEK7 molecular glue degrader, designed to treat inflammatory diseases.
Read More
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