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Home » Topics » Disease categories and therapies » Cardiovascular

Cardiovascular
Cardiovascular RSS Feed RSS

omniasecure defib lead

FDA approves Medtronic Omniasecure defib lead

June 13, 2025
By Annette Boyle
Medtronic plc received U.S. FDA approval for its Omniasecure defibrillation lead for placement in the right ventricle to treat arrhythmias. Medtronic said the lead is the smallest made at 4.7 French or 1.6 mm, making it suitable for individuals as young as age 12 and others with smaller anatomies, particularly women.
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South Korea flag with stock chart, gold coins

Korea biotech roundup: four financings, six R&D deals mid-June

June 13, 2025
By Marian (YoonJee) Chu
No Comments
Four biotech companies from South Korea announced new or planned financings mid-June, including GC Genome Corp. Rznomics Inc., G2Gbio Inc. and Mezzion Pharma Co. Ltd. Six major mid-June deals included R&D pacts between Y-Biologics Inc. and Crosspoint Therapeutics, Daewoong Pharmaceutical Co. Ltd. and Salipro Biotech AB, Next & Bio Inc. and GC Cell Corp., Galux Inc. and Hanall Biopharma Co. Ltd., Celltrion Inc. and Onconic Therapeutics Inc., and SK Plasma Co. Ltd. and Aimedbio Inc.
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Cardiovascular

Shanghai Qilu Pharmaceutical describes new apolipoprotein A inhibitors

June 13, 2025
Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. has divulged compounds acting as apolipoprotein A (ApoA; LPA) inhibitors reported to be useful for the treatment of hyperlipidemia, coronary heart disease, ischemic stroke and myocardial infarction.
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Digital cardiology illustration
Cancer

ICG-001 protects heart from doxorubicin-induced cardiotoxicity

June 13, 2025
No Comments
Doxorubucin is an effective therapeutic in cancer treatment, but it can cause cardiotoxicity and damage the mitochondrial machinery. A new patient-derived and mitochondria-rich human induced pluripotent stem cell derived-cardiomyocyte (hiPSC-CM) model protected by dexrazoxane was developed.
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Boston Scientific Farapulse PFS system

What's the secret behind Boston Sci's successful product launches?

June 12, 2025
By Annette Boyle
Boston Scientific Corp.’s Farapulse pulsed field ablation system racked up more than $1 billion in revenue in its first year; its Watchman left atrial appendage occluder holds more than 90% of the market. How does the company choose and position its products for such astonishing success?
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Global market charts

The Ps and Qs of challenging a market leader

June 12, 2025
By Annette Boyle
Med-tech veterans advised companies looking to launch new products in fields with dominant players to mind their 'Ps and Qs,' but not the ones your mother drilled in childhood. Rather than good manners, they urged competitors attending Device Talks Minnesota to ensure they had the right people, product, proof, pace and quality control.
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Fineheart Flowmaker

Fineheart pursues FIH study of Flowmaker fully implanted heart pump

June 11, 2025
By Shani Alexander
Fineheart SA will soon begin a first-in-human study of Flowmaker, its fully implantable left ventricular assist device, in France, after receiving authorization from the French National Agency for the Safety of Medicines and Health Products to initiate the trial.
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shockwave-device-c2-plus.jpg

IVL innovators: How to challenge a market leader

June 11, 2025
By Annette Boyle
What does it take to create space in a market dominated by a single player? Three challengers to Johnson & Johnson's Shockwave shared their strategies for gaining traction in intravascular lithotripsy (IVL) at the Device Talks meeting June 11 in Minneapolis.
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AI-generated illustration of heart and metabolic impact

Deep Apple signs big Novo deal for cardiometabolic small molecules

June 11, 2025
By Lee Landenberger
No Comments
Deep Apple Therapeutics Inc. could bring in as much as $812 million in a new collaboration and license deal with Novo Nordisk A/S. The total includes an unspecified up-front payment, research costs and milestones. The two plan to develop and commercialize oral small molecules for non-incretin G-protein coupled receptor targets for treating cardiometabolic diseases, including obesity, a core specialty for Novo Nordisk.
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Molecular research art concept
Inflammatory

Monte Rosa’s molecular glue degrader MRT-8102 gains IND clearance for inflammatory conditions

June 11, 2025
No Comments
Monte Rosa Therapeutics Inc. has gained IND clearance from the FDA for MRT-8102, a NEK7-directed molecular glue degrader being developed to treat inflammatory conditions linked to NLRP3, IL-1β and IL-6 dysregulation.
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