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Home » Topics » Disease categories and therapies » Cardiovascular

Cardiovascular
Cardiovascular RSS Feed RSS

Heart, DNA and ECG

Nuevocor draws $45M series B for gene therapy in rare heart disease

May 6, 2025
By Nuala Moran
No Comments
Nuevocor Pte. Ltd. has closed a $45 million series B, enabling it to move lead gene therapy NVC-001 into the clinic in the treatment of an inherited form of cardiomyopathy.
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Durvena
Patents

Durvena strengthens vein grafts to reduce post-surgery failures

May 5, 2025
By Simon Kerton
In what represents the first patenting to emerge in the name of Durvena Inc., co-founder and CEO John Ashley describes the development of a treatment for vein grafts that strengthens the graft and reduces the occurrence of intimal hyperplasia that commonly leads to graft failure.
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Novo Nordisk semaglutide pill

Oral GLP-1 Wegovy chases approval in obesity

May 5, 2025
By Lee Landenberger
No Comments
The U.S. FDA has accepted the NDA for an oral formulation of Novo Nordisk A/S’s Wegovy (semaglutide) in treating obesity. If approved, the daily pill will be the first oral GLP-1 for treating chronic weight management. So far, however, it has been injectables leading the way to approval.
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Test tube, dropper, DNA illustration
Cardiovascular

Mammoth nominates development candidate for FCS and severe hypertriglyceridemia

May 5, 2025
No Comments
Mammoth Biosciences Inc. has nominated its first clinical development candidate – MB-111 – a potential one-time treatment for patients with very high triglycerides, including familial chylomicronemia syndrome (FCS) and severe hypertriglyceridemia. IND-enabling studies are on track to begin this year.
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Single Shot PVI
Heart Rhythm 2025

PULSAR gives Kardium legs in PFA horse race

May 2, 2025
By Annette Boyle
With strong one-year results from the PULSAR trial, Kardium Inc. could soon be jockeying for third place in the race for pulsed field ablation market share. Boston Scientific Corp. clearly won the roses, with Medtronic plc solidly positioned to place, but the show spot – previously called as a battle between Johnson & Johnson and Abbott Laboratories – could go to this Canadian dark horse.
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3D heart in chest

Oh them REMS: Cytokinetics heart-hit with FDA delay

May 2, 2025
By Randy Osborne
Wall Street immediately set to weighing the long-term import of Cytokinetics Inc.’s regulatory delay with aficamten, but the short-term impact was evident, as shares (NASDAQ:CYTK) dipped to close May 2 at $37.35, a loss of $5.57 or 13%.
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Cardiovascular

Fauna Bio describes new 5-HT3 receptor antagonists

May 2, 2025
Fauna Bio Inc. has identified 5-HT3 receptor antagonists reported to be useful for the treatment of cardiovascular and respiratory disorders.
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Device in heart

FDA expands Edwards’ TAVR to asymptomatic severe aortic stenosis

May 1, 2025
By Annette Boyle
In a significant boost to the Edwards Lifesciences Corp. Sapien 3 platform’s market opportunity, the U.S. FDA approved use of the transcatheter aortic valve replacement in patients with asymptomatic aortic stenosis.
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Heart scientific overlay
Heart Rhythm 2025

Field Medical, Adagio look to VT for break out indication

April 30, 2025
By Annette Boyle
Presentations at Heart Rhythm 2025 for Field Medical Inc. and Adagio Medical Holdings Inc. demonstrated success in two very different types of ablation for ventricular tachycardia, potentially offering new options for a harder-to-treat type of arrhythmia.
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3D heart in chest
Heart Rhythm 2025

PFA continues to set EP hearts aflutter

April 29, 2025
By Annette Boyle
No Comments
Pulsed field ablation dominated discussions and scientific sessions at Heart Rhythm 2025 in San Diego with researchers and manufacturers touting new applications in persistent atrial fibrillation, atrial flutter and addressing specific challenges for existing systems.
Read More
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