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BioWorld - Wednesday, June 18, 2025
Home » Topics » Disease categories and therapies » Cardiovascular

Cardiovascular
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Aortic aneurysm illustration
Cardiovascular

GPX4 is a therapeutic target for abdominal aortic aneurysm

April 29, 2025
Researchers have identified glutathione peroxidase 4 (GPX4) as a therapeutic target in abdominal aortic aneurysm, a vascular disease characterized by permanent and focal dilatation of the abdominal aorta, with a mortality rate of up to 85% in case of rupture.
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PerQseal Elite

Vivasure Perqseal vascular closure system lands CE mark

April 28, 2025
By Shani Alexander
Vivasure Medical Ltd. received CE mark approval for its Perqseal Elite vascular closure system which manages bleeding complications associated with large-bore arterial vessel closure. The sutureless, fully bioresorbable device has the potential to reduce problems associated with traditional closure methods in patients undergoing complex structural heart procedures.
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Heart scientific overlay
Heart Rhythm 2025

HRA/ACC release same-day discharge guidance for cardiac ablation

April 28, 2025
By Annette Boyle
The Heart Rhythm Society and American College of Cardiology published guidance for same-day discharge of cardiac ablation patients during Heart Rhythm 2025, the society’s annual meeting, which was held in San Diego April 26-27.
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Screen on Fitbit Sense reads "Take heart rhythm assessment"
Heart Rhythm 2025

Fitbit analysis predicts hospitalizations

April 28, 2025
By Annette Boyle
Using step counts and heart rate readings from Google’s Fitbit devices, a machine learning model accurately predicted the risk of hospitalization, a study presented at Heart Rhythm 2025 found. The study used data from participants in the National Institutes of Health’s All of Us research program.
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IPO, coins, financial chart

China pharma migration: Hengrui greenlighted for Hong Kong IPO

April 28, 2025
By Marian (YoonJee) Chu
Jiangsu Hengrui Pharmaceuticals Co. Ltd. is the latest mainland China pharmaceutical company to seek a capital raise on the Hong Kong stock exchange, winning clearance April 28 from the China Securities Regulatory Commission to float new H-shares.
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Hematologic

Vaccination approach prevents clotting without increased bleeding

April 28, 2025
A recent study by researchers from Texas A&M University presented a new vaccine designed to target the ligand-binding domain of the serotonin 2A receptor (5-HT2AR), which resides in the second extracellular loop (EL2) and was previously identified as the key region for receptor activation. The new candidate, called EL2-5HTVac, was shown to provide a long-lasting and selective therapeutic approach to avoid increased bleeding risk complications.
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Blood pressure monitor
Cardiovascular

Chinese IND clearance for Rona′s AGT-targeting siRNA drug for hypertension

April 25, 2025
Rona Therapeutics Co. Ltd. has obtained IND clearance from China′s National Medical Products Administration (NMPA) for RN-1871, a small interfering RNA (siRNA) drug targeting angiotensinogen (AGT) for hypertension.
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Boston Scientific Farapulse PFS system
HRS 2025

Boston Sci expects $200M tariff hit, still raises guidance

April 24, 2025
By Annette Boyle
Growth in the first quarter for Boston Scientific Corp.’s blockbuster products, Farapulse and Watchman, pushed the company well over analysts’ expectations and gave management confidence to raise its guidance for the year to 15% to 17% up from 12.4% to 14.5%, despite a projected $200 million in tariff impacts.
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AMT Medical ELANA Heart Bypass system

AMT Medical raises $25M for its Elana heart bypass system

April 24, 2025
By Shani Alexander
AMT Medical BV raised $25 million in a series B financing round for its Excimer Laser Assisted Non-Occlusive Anastomosis heart bypass system. The funds will go towards clinical trials and regulatory approval for its sutureless coronary bypass technology designed to replace traditional open-heart bypass surgery.
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China in red on globe
Chinabio 2025

US capital crunch pushes China biotechs to roundabout financings

April 24, 2025
By Marian (YoonJee) Chu
Tightening of U.S. regulation and capital is leading Chinese biotechs to alternative and new models of financing, ranging from cross-border licensing deals, M&As, the so-called newco model and overseas listings.
Read More
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