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BioWorld - Tuesday, April 7, 2026
Home » Topics » Disease categories and therapies » Cardiovascular

Cardiovascular
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Colorful illustration of the heart
Cardiovascular

Financing at Immutrin to advance antibody for ATTR cardiomyopathy

March 24, 2026
No Comments
Immutrin Ltd. has successfully raised £65 million ($87 million) in series A financing to advance its lead asset through clinical proof of concept in ATTR cardiomyopathy. Immutrin’s novel antibody selectively binds to amyloid fibrils and is engineered to deplete amyloid deposits in tissue via a targeted and coordinated immune response.
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AI startup art concept

How to grow a startup in the AI era: MedTech Spotlight Korea 2026

March 23, 2026
By Marian (YoonJee) Chu
No Comments
AI and advanced biotechnology are reshaping South Korea’s med-tech sector, but great technology alone is not enough to build a successful medical device company, speakers said at MedTech Innovator’s Medtech Spotlight: New Impact Korea 2026.
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Imperative Care Symphony

Imperative secures $100M for thromboembolic technologies

March 18, 2026
By Shani Alexander
No Comments
Imperative Care Inc. secured $100 million through an oversubscribed convertible note financing round to support commercialization of its stroke and vascular thrombectomy technologies. The round was co-led by new investors Elevage Medical Technologies and Perceptive Advisors alongside existing investor Catalio Capital Management LP. Also participating were new backers Longaeva Partners LP and Brown Advisory, with continued support from existing investors, including Ally Bridge Group and Bain Capital Life Sciences.
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GLP-1 capsule

Structure’s oral GLP-1 data mark bullish year for obesity pills

March 17, 2026
By Marian (YoonJee) Chu
No Comments
The GLP-1 fight has moved from injectables to pills, and Structure Therapeutics Inc. is in the ring with phase III-ready aleniglipron. According to the Bay Area biotech, its oral once-daily glucagon-like peptide-1 (GLP-1) drug candidate, aleniglipron, demonstrated an absolute weight loss of “up to 39 pounds” in the 44-week Access II trial.
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Screenshot of “Kill the Clipboard” app

Samsung is adding trials and EHR access to Galaxy devices

March 17, 2026
By Marian (YoonJee) Chu
No Comments
Samsung Electronics Co. Ltd. is partnering with Verily Life Sciences LLC, an Alphabet Inc. company, and B.well Connected Health to turn Samsung Galaxy phones and smart watches into the “front door” of U.S. health care.
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Screenshot of “Kill the Clipboard” app

Samsung is adding trials and EHR access to Galaxy devices

March 11, 2026
By Marian (YoonJee) Chu
No Comments
Samsung Electronics Co. Ltd. is partnering with Verily Life Sciences LLC, an Alphabet Inc. company, and B.well Connected Health to turn Samsung Galaxy phones and smart watches into the “front door” of U.S. health care.
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Taiwan President Lai Ching-te presides over the seventh meeting of the Healthy Taiwan Promotion Committee.

Taiwan to invest $752M in biopharma security over four years

March 10, 2026
By Marian (YoonJee) Chu
No Comments
Taiwan plans to invest NT$24 billion (US$752 million) over four years to bolster national biosecurity, expand domestic pharmaceutical production and safeguard against global supply chain volatility.
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Mixed phase II results still point to path forward for AISA-021

March 10, 2026
By Tamra Sami
No Comments
Although Aisa Pharma Inc’s cilnidipine (AISA-021) failed to meet the primary endpoint, multiple secondary endpoints showed statistically significant improvement in treating sclerosis-associated Raynaud's phenomenon, potentially positioning the drug for a phase III program in a disease with no approved oral therapies globally.
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Hand pointing at digital M&A screen

Medtronic continues M&A momentum with $550M Scientia Vascular buy

March 10, 2026
By Shani Alexander
No Comments
Medtronic plc has agreed to buy Scientia Vascular Inc. for $550 million, as it makes good on its promise to embark on more strategic acquisitions this year. The acquisition will bolster its neurovascular business as it adds a portfolio of guidewires and catheters, which uses Scientia’s microfabrication technology to simplify complex neurovascular procedures.
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Illustration showing the different types of muscle cells
Neurology/psychiatric

TN-301 restores muscle and cardiac function in DMD models

March 10, 2026
No Comments
In Duchenne muscular dystrophy (DMD), deficiency of dystrophin leads to cardiomyocyte membrane instability, abnormal calcium influx, and progressive fibrotic remodeling of cardiac tissue. Histone deacetylase 6 (HDAC6) contributes to disease progression by regulating cytoskeletal dynamics and proteostasis in dystrophic muscle cells. Consequently, inhibition of HDAC6 represents a potential therapeutic strategy for addressing both the skeletal and cardiac manifestations of DMD.
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