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Home » Topics » Disease categories and therapies » Cardiovascular

Cardiovascular
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Shockwave IVL
EuroPCR 2025

Shockwave IVL system continues to make waves

May 28, 2025
By Shani Alexander
Shockwave Medical Inc. is confident that its intravascular lithotripsy (IVL) system can continue to dominate the market for calcium modification even as other technologies emerge, chief medical officer Nick West told BioWorld.
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EBR Wise CRT system

EBR Systems raises $36M to sell Wise CRT therapy

May 28, 2025
By Tamra Sami
EBR Systems Inc. raised AU$55.9 million (US$36 million) to commercialize its Wise cardiac resynchronization therapy system following U.S. FDA approval in April of the wireless, endocardial pacing system to stimulate the heart’s left ventricle.
Read More
Heart and DNA

Houston, a problem: Rocket death in Danon stalls phase II program

May 27, 2025
By Randy Osborne
No Comments
Rocket Pharmaceuticals Inc. CEO Gaurav Shah said his firm is investigating how its gene therapy for Danon disease may have created an “unexpected and paradoxical” effect that led to problems for a phase II patient who ultimately died.
Read More
Heart scientific overlay
Cardiovascular

Frontera’s FT-017 exerts robust activity in hypertrophic cardiomyopathy

May 27, 2025
No Comments
Frontera Therapeutics Inc. has developed FT-017, an adenovirus-associated vector(AAV)-based gene therapy that carries a human MYBPC3 optimized codon, for the treatment of hypertrophic cardiomyopathy (HCM).
Read More
Device in heart
EuroPCR 2025

Edwards' data shows benefits of early intervention in aortic stenosis

May 23, 2025
By Shani Alexander
Edwards Lifesciences Corp. released new economic and clinical data on severe aortic stenosis (AS) demonstrating intervening in a patient with the disease before symptoms develop can reduce costs to the health care system by $36,000. Data also shows earlier intervention can also lead to fewer follow-ups and hospitalizations for heart failure, after treatment.
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Human heart within crosshairs

Tectonic, Tenax, others aim for shift in heart failure

May 23, 2025
By Randy Osborne
No Comments
News from Tectonic Therapeutic Inc. in January took away some of Wall Street’s jitters about the relaxin pathway brought about by Eli Lilly and Co.’s recent moves, but another big pharma player – Astrazeneca plc – is still providing suspense in pulmonary hypertension in heart failure with preserved ejection fraction.
Read More
TRiCaresTopaz
EuroPCR 2025

Tricares Topaz valve significantly reduces tricuspid regurgitation

May 22, 2025
By Shani Alexander
Data from the first-in-human study of Tricares SAS Topaz transcatheter tricuspid valve replacement (TTVR) system, showed it significantly reduced tricuspid regurgitation (TR) in patients treated with the device. The early clinical data at 30 days demonstrated that all patients implanted with Topaz were at a TR grade ‘none’ (0+) or ‘mild’ (1+) following the procedure.
Read More
Hands holding torn contract

Medtronic aims to sweeten appeal by unloading diabetes unit

May 21, 2025
By Annette Boyle
Medtronic plc revealed plans to spin off its underperforming diabetes unit as a separate public company during its fourth quarter 2025 earnings call May 21. The company expects to complete the separation within 18 months.
Read More
3-30-Medtronic-Symplicity-Spyral.png
EuroPCR 2025

Medtronic reveals data on benefits of RDN system

May 21, 2025
By Shani Alexander
Medtronic plc revealed data at the EuroPCR conference which showed there was a significant, safe and sustained blood pressure reduction in patients treated with its Spyral renal denervation system who meet European recommended guidelines criteria over a three-year period.
Read More
Elixir Medical DynamX
EuroPCR 2025

Dynamx bioadaptor superior to Resolute Onyx DES

May 21, 2025
By Shani Alexander
Three-year data from Elixir Medical Corp.’s Bioadaptor randomized controlled trial showed that patients with coronary artery disease treated with its Dynamx coronary drug-eluting bioadaptor system continued to see lower adverse events rates compared to those treated with Medtronic plc’s Resolute Onyx drug-eluting stent .
Read More
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