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BioWorld - Tuesday, December 9, 2025
Home » Topics » Disease categories and therapies » Dermatologic

Dermatologic
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Dermatologic

Hangzhou Bio-Creativity Pharma-Tech patents new PI3Kγ inhibitors for atopic dermatitis

Jan. 24, 2025
Hangzhou Bio-Creativity Pharma-Tech Co. Ltd. has disclosed phosphatidylinositol 3-kinase γ (PI3Kγ) inhibitors reported to be useful for the treatment of atopic dermatitis.
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Endocrine/metabolic

Kexing Biopharm highlights progress across pipeline

Jan. 24, 2025
Kexing Biopharm Co. Ltd. has outlined progress in its cachexia and autoimmune pipelines, built upon its Kx-Body antibody technology platform and Kx-Fusion fusion protein technology platform.
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White strand of DNA
Biomarkers

Wnt/PCP signaling mediators identified as new markers in yellow nail syndrome

Jan. 20, 2025
Researchers from Tel Aviv Sourasky Medical Center presented data from a study that aimed to investigate the genetic mechanisms underlying yellow nail syndrome (YNS), a rare disorder characterized by three features, namely yellow dystrophic nails, lymphedema and chronic lung disease.
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Mixed reality burn tool

New mixed-reality tool created to transform burn care

Jan. 17, 2025
By Shani Alexander
The U.K.’s Buckinghamshire NHS Trust has partnered medical technology design experts from Team Consulting Ltd. to create a tool that can transform burn care treatment. The concept training tool incorporates mixed reality which maps ‘custom digital burns’ onto a mannequin to enable surgeons to explore a diverse range of burn types and patient profiles and deliver better outcomes.
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Dermatologic

Targeting GluK2 combats mast cell activation and skin inflammation

Jan. 15, 2025
A recent study published in Science Translational Medicine has examined a new approach to address inflammatory skin diseases, such as dermatitis and rosacea, by focusing on a specific glutamate receptor in mast cells.
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Gilead, Leo Pharma join in $1.7B deal for STAT6 program

Jan. 13, 2025
By Nuala Moran
Gilead Sciences Inc. is moving further into inflammatory diseases in a potential $1.7 billion deal with Leo Pharma A/S around a preclinical oral signal transduction and activator of transcription 6 (STAT6) program that the Danish dermatology specialist has been working on since 2018.
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Phio flies on complete responses in phase I skin cancer trial

Jan. 13, 2025
By Karen Carey
Shares of Phio Pharmaceuticals Corp. soared 291% Jan. 13 on news that two patients with cutaneous squamous cell carcinoma had a complete response following treatment with the company’s Intasyl siRNA gene silencing candidate PH-762.
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Inflammatory

Gilead and Leo Pharma partner on oral STAT6 program

Jan. 13, 2025
Gilead Sciences Inc. and Leo Pharma A/S have established a strategic partnership to accelerate the development and commercialization of Leo’s small-molecule oral STAT6 programs for the treatment of inflammatory diseases.
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Jasper posts positive early data as stock drops

Jan. 8, 2025
By Lee Landenberger
Despite positive preliminary data from its early stage study of treating hives, Jasper Therapeutics Inc. saw its stock drop dramatically on Jan. 8. Results were from the ongoing phase Ib/IIa study of the monoclonal antibody and lead candidate briquilimab in treating chronic spontaneous urticaria, often referred to as hives. The results showed clinical responses across several of the dosing cohorts. The treatment also displayed a favorable safety profile.
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Dermatologic

Nimbus Therapeutics patents new 15-hydroxyprostaglandin dehydrogenase inhibitors

Jan. 8, 2025
Nimbus Therapeutics LLC has disclosed 15-hydroxyprostaglandin dehydrogenase inhibitors reported to be useful for the treatment of alopecia, muscle atrophy and more.
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