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Home » Topics » Disease categories and therapies » Diabetes

Diabetes
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GLP-1 receptor, inactive form vs. active complex with an agonist (semaglutide) and G-proteins

Fractyl, Bariendo developing off-ramp for post-GLP-1 maintenance

June 4, 2025
By Annette Boyle
Far from eliminating the need for weight-loss procedures, glucagon-like peptide-1 receptor agonists could drive more people to seek them out. At least that’s what Fractyl Health Inc. and Bariendo Inc. hope, and they have strong evidence to support their case with a recent meta-analysis showing that individuals discontinuing the popular weight loss medications regain all their weight and more within two years.
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Hands holding torn contract

Medtronic aims to sweeten appeal by unloading diabetes unit

May 21, 2025
By Annette Boyle
Medtronic plc revealed plans to spin off its underperforming diabetes unit as a separate public company during its fourth quarter 2025 earnings call May 21. The company expects to complete the separation within 18 months.
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HKEX exterior

China’s Pegbio launches HK$300M Hong Kong IPO

May 20, 2025
By Tamra Sami
No Comments
China’s Pegbio Co. Ltd. launched its IPO on the Hong Kong stock exchange May 19, to raise up to HK$300.82 million (US$38.4 million) to advance visepegenatide (PB-119), its glucagon-like peptide 1 (GLP-1) receptor agonist.
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HKEX exterior

China’s Pegbio launches HK$300M Hong Kong IPO

May 19, 2025
By Tamra Sami
No Comments
China’s Pegbio Co. Ltd. launched its IPO on the Hong Kong stock exchange May 19, to raise up to HK$300.82 million (US$38.4 million) to advance visepegenatide (PB-119), its glucagon-like peptide 1 (GLP-1) receptor agonist.
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Kakao Pasta app

Kakao Healthcare brings CGM app to Japan

May 16, 2025
By Marian (YoonJee) Chu
Step aside, Marco Polo: Kakao Healthcare Corp. plans to bring PASTA to Japan. PASTA is Kakao's AI-based continuous glucose monitoring (CGM) management mobile application, which will be available in Japan through a new subsidiary as the health care company works to expand its global presence.  
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urine testing device
Patents

Urine-testing device turns toilets into health trackers

May 16, 2025
By Simon Kerton
In what represents just the company’s third PCT filing, Houston-based Starling Medical Inc.’s co-founders, Hannah McKenney and William Hendricks, seek to gain further protection for their at-home urine diagnostic patient-monitoring platform that eliminates the traditional use of catching containers and dipsticks.
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Freestyle Libre 3 sensor with smartphone app

Abbott studies show CGM users have fewer hospitalizations

May 15, 2025
By Annette Boyle
A pair of studies published in Diabetologia demonstrate that use of continuous glucose monitors (CGMs) reduces hospitalizations in people with type 1 diabetes and in those with type 2 diabetes who use insulin compared to use of capillary blood glucose monitoring. Abbott Laboratories’s REFLECT real-world studies showed that use of its Freestyle Libre CGMs reduced the severity of cardiovascular conditions associated with diabetes and, consequently, led to fewer in-patient stays.
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Pills, bottle, scale and-measuring tape

Septerna joins a $2.2B obesity deal with Novo

May 14, 2025
By Lee Landenberger
No Comments
In a deal that could top out at about $2.2 billion, Septerna Inc. is getting $200 million up front from Novo Nordisk A/S in a collaboration to develop oral treatments for obesity, type 2 diabetes and other cardiometabolic indications. There will be four programs for discovering, developing and commercializing small molecules targeting G protein-coupled receptors, which includes GLP-1, GIP and glucagon receptors, with both companies putting their shoulders to conducting research from discovery to choice of candidate.
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Businessman and IPO virtual screen

Three med-tech IPOs on the horizon

May 13, 2025
By Annette Boyle
April may not have brought rain to med-tech, but tariffs and financial uncertainty certainly dampened the enthusiasm for IPOs. With those clouds lifting, three companies – Hinge Health Inc., Capsovision Inc., and Omada Health Inc. – appear ready to flower in May, potentially a harbinger of a return to the brisk pace for med-tech IPOs seen in the opening weeks of 2025 when eight companies raised nearly $1 billion.
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Hands holding arrow-shaped puzzle pieces

Diabetes segment reports good news all around

May 7, 2025
By Annette Boyle
Senseonics Holdings Inc. and Sequel Med Tech LLC revealed plans to develop an automated insulin delivery system using the Eversense one-year, implantable continuous glucose monitoring system to increase flexibility for people with type 1 diabetes.
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