Perianal fistulas in Crohn's disease represent a severe complication of the disease. Researchers used a recently established Crohn's perianal fistula rat model to test a novel and proprietary biodegradable nanofiber-hydrogel composite (NHC) loaded with rat adipose-derived stem cells (ADSCs).

Sosei and Kallyope have entered a strategic research collaboration to identify and validate novel G protein-coupled receptor (GPCR) targets with a goal of creating new drug discovery programs in the area of gastrointestinal diseases.