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BioWorld - Monday, January 12, 2026
Home » Topics » Disease categories and therapies » Hematologic

Hematologic
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Imara reports phase IIa data on IMR-687 in sickle cell disease

Jan. 7, 2021
Sickle cells

Imara wraps up a phase IIa in sickle cell with mixed results

Jan. 6, 2021
By Lee Landenberger
Imara Inc. reported a mixed bag of phase IIa study data for its lead candidate, IMR-687, for treating sickle cell disease in adults, bringing an end to a study that the company found cumbersome and that eventually stung its stock.
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Novel thrombosis mouse models using Jak2 platelet conditional knockout

Jan. 4, 2021

Transgenic mice allow study of erythroferrone overexpression

Dec. 29, 2020

Geron initiates phase III study of imetelstat in myelofibrosis refractory to JAK inhibitors

Dec. 28, 2020

Enrollment ongoing in phase II study of PHA-022121

Dec. 28, 2020

DISC-A demonstrates efficacy in low hepcidin rat model

Dec. 28, 2020

DISC-0974 decreases hepcidin and increases transferrin saturation in inflammation models

Dec. 28, 2020

FDA places clinical hold on uniQure's hemophilia B gene therapy program

Dec. 23, 2020

PKLR activator mitapivat shows promising preclinical data in murine hereditary spherocytosis

Dec. 23, 2020
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