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BioWorld - Monday, March 30, 2026
Home » Topics » Disease categories and therapies » Hematologic

Hematologic
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bluebird bio temporary suspends studies of LentiGlobin gene therapy for SCD

Feb. 17, 2021

Bluebird suspends sickle cell studies amid blood cancer concerns

Feb. 16, 2021
By Michael Fitzhugh
Shares of Bluebird Bio Inc. (NASDAQ:BLUE) fell 37.8% to $28.44 on Feb. 16 as the company temporarily suspended two trials of its experimental gene therapy for sickle cell disease, Lentiglobin (BB-1111), while investigating one unexpected case of acute myeloid leukemia (AML) and another of myelodysplastic syndrome among participants in a phase I/II study of the candidate, called HGB-206. A second patient experienced MDS in 2018.
Read More

New phase I/II trial investigates JSP-191 in sickle cell disease

Feb. 12, 2021

Enrollment ongoing in phase III study of LNP-023 in adults with PNH with residual anemia

Feb. 11, 2021

KalVista releases phase II data on KVD-900 as oral on-demand treatment for HAE

Feb. 9, 2021

Phase I/II results for TAK-754 gene therapy in severe hemophilia A

Feb. 8, 2021

Updated patient eligibility and first-in-human data for BAY-2599023

Feb. 8, 2021

SerpinPC found useful in patients with severe hemophilia

Feb. 8, 2021

Thrombin trivalent inhibitors inspired by native peptidic inhibitors from hematophagous arthropods

Feb. 8, 2021

PHA-121 demonstrates promising safety and PK profile in phase I study

Jan. 29, 2021
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