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BioWorld - Wednesday, April 29, 2026
Home » Topics » Disease categories and therapies » Hematologic

Hematologic
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Globe showing China

First ever comprehensive blood disease research platform to be built for China

Dec. 16, 2019
By David Ho
HONG KONG – Boston-based consulting firm Analysis Group Inc. will be working with China’s Institute of Hematology & Blood Diseases Hospital (IHBDH) on developing a first-of-its-kind blood disease research platform. The National Longitudinal Cohort of Hematological Diseases in China (NICHE) is set to hold the information of more than 10,000 patients across China.
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Results reported from ongoing phase I study of FT-4202

Dec. 16, 2019

Phase II trials of concizumab show clinical proof of concept for bleeding prevention in hemophilia

Dec. 16, 2019

Novel FVIII mimetic bispecific antibody Mim8 exhibits preclinical efficacy against hemophilia A

Dec. 12, 2019
Red blood cells, DNA

ASH 2019: A roundup of four days of insight from Orlando

Dec. 11, 2019
By Lee Landenberger
ORLANDO, Fla. – The world’s biggest and certainly most lavish hematology gathering, the 61st American Society of Hematology conference, just ended in Orlando, having brought 30,024 people from 25 countries to glory in Florida sunshine, if they got outside, but mostly to bask in the discipline’s most up-to-the-minute data.  The amount of research was staggering, with 5,978 abstracts available for review. Key themes included work aimed at overcoming obstacles to CAR T therapy, new progress in preventing and treating venous thromboembolism, moves to address health care disparities and new developments in the care of sickle cell diseases. Late-breakers highlighted new data on Blincyto (blinatumomab, Amgen Inc.), Sanofi SA's sutimlimab, azacitidine and Darzalex (daratumumab, Janssen Biotech Inc.). 
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Conference data for Dec. 11, 2019: American Society of Hematology

Dec. 11, 2019
New and updated preclinical and clinical data presented by biopharma firms at the 61st American Society of Hematology annual meeting in Orlando, Fla.
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Pfizer gives details on the discovery of novel noncovalent modulator of hemoglobin

Dec. 11, 2019
ASH 2019

In all Candor, Darzalex has positive data

Dec. 10, 2019
By Lee Landenberger
ORLANDO, Fla. – As the enormous American Society of Hematology annual meeting wound down, the Janssen Pharmaceutical Cos. of Johnson & Johnson released phase III data showing that adding Darzalex to carfilzomib and dexamethasone, compared to carfilzomib and dexamethasone alone, significantly improved progression-free survival in patients with relapsed/refractory multiple myeloma.
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ASH 2019

With reduced toxicity, can HSCT make it to Hall of Fame?

Dec. 10, 2019
By Anette Breindl
ORLANDO, Fla. – Two preclinical presentations at the 61st American Society of Hematology (ASH) annual meeting could pave the way for using hematopoietic stem cell transplants (HSCT) in patients who are currently too sick to tolerate the procedure, as well as in indications where its toxicities preclude its use.
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Sickle cell disease
ASH 2019

‘Multiple ways’ of fighting once-incurable sickle cell disease

Dec. 10, 2019
By Anette Breindl
ORLANDO, Fla. – At the 61st ASH annual meeting late-breaking abstracts session, researchers from Boston Children’s Hospital reported that three adult patients who had received an autologous transplant of gene-edited hematopoietic stem cells lacking BCL11A produced high levels of functional hemoglobin and had reduced disease symptoms for at least eight months after transplantation. 
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