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BioWorld - Thursday, April 30, 2026
Home » Topics » Disease categories and therapies » Hematologic

Hematologic
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CRISPR-Cas9
ASH 2019

Gene editing can move cell therapy from biplane to Boeing era

Dec. 9, 2019
By Anette Breindl
ORLANDO, Fla. – “The Wright brothers showed that you could fly a plane, but it wasn’t very far and it wasn’t very safe,” Wendell Lim told his audience at the 61st American Society of Hematology (ASH) annual meeting this weekend. “That’s where cell therapy is now.”
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ASH 2019

Genentech showcases new data on CD20-CD3 bispecific for tough-to-treat lymphomas

Dec. 9, 2019
By Michael Fitzhugh
ORLANDO, Fla. - Chimeric antigen receptor T (CAR T) cells have proved to be a major advance in treating patients with refractory B-cell malignancies so far. But, often, in approaching those issues "we solve one and we create another," Stephen Schuster, a doctor at the Abramson Cancer Center at the University of Pennsylvania in Philadelphia, told reporters at the 61st American Society of Hematology (ASH) annual meeting Saturday.
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Positive topline data reported from phase II pozelimab in patients with PNH

Dec. 9, 2019
Cancer stem cells

Omeros touts pivotal data on HSCT-TMA candidate, shielding details

Dec. 4, 2019
By Michael Fitzhugh
A pivotal trial of Omeros Corp.'s narsoplimab, an investigational therapy for an occasional but serious complication of hematopoietic stem cell transplant (HSCT), found that just one dose was enough to deliver a beneficial effect in more than half the study's high-risk participants, meeting the study's primary endpoint.
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Preliminary phase II results for PTG-300 in transfusion-dependent beta-thalassemia

Dec. 4, 2019

Holding out for a hero: Protagonist takes a market hit

Dec. 3, 2019
By Lee Landenberger
Protagonist Therapeutics Inc. stock (NASDAQ:PTGX) nosedived 47% on Tuesday after the company released preliminary results from its phase II open-label study of PTG-300, an injectable hepcidin mimetic to treat patients with transfusion-dependent beta-thalassemia.  
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Funding supports LUNAC-led project to develop next-generation anticoagulant

Dec. 3, 2019

Akari announces trial design for pivotal phase III study of nomacopan in pediatric HSCT-TMA

Dec. 3, 2019

Shenzhen Salubris Pharmaceuticals identifies new PAR-4 antagonists

Dec. 2, 2019

La Jolla re-evaluates its development of LJPC-401 due to mixed clinical results

Nov. 27, 2019
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