To develop a safe and effective respiratory syncytial virus (RSV) vaccine for use in early life, Boston Children's Hospital scientists and their collaborators developed CAF-08, a liposomal formulation consisting of combined TLR7 (3M-052) and Mincle (trehalose-6,6-dibehenate [TDB]) agonists and the RSV pre-F antigen.
Blue Water Vaccines (BWV) will attempt to present monkeypox antigens within its norovirus shell and protrusion (S&P) virus-like particle (VLP) platform to develop a novel monkeypox vaccine.
The U.S. Department of Defense (DoD) is awarding Codagenix USD 4.4 million for further development of its next-generation tetravalent dengue vaccine candidate CodaVax-DENV.
International AIDS Vaccine Initiative (IAVI) and Merck & Co. scientists have developed a SARS-CoV-2 vaccine using the vesicular stomatitis virus (VSV) chimeric virus approach, wherein VSV was modified by substituting the VSV G surface glycoprotein gene with a coding sequence for the SARS-CoV-2 spike (S) glycoprotein.
Researchers from University of Miami Miller School of Medicine reported preclinical data for ZyVersa Therapeutics' novel humanized IgG4 monoclonal antibody targeting apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC), named IC-100.
A first-of-its-kind comprehensive map of the network of connections in the human immune system has uncovered previously unknown interactions and filled in gaps in understanding why approved immunotherapies work in some patients and not others.
A first-of-its-kind comprehensive map of the network of connections in the human immune system has uncovered previously unknown interactions and filled in gaps in understanding why approved immunotherapies work in some patients and not others.
Scientists from the University of Washington and the Fred Hutchinson Cancer Research Center and their collaborators have described the generation of self-assembling nanoparticles displaying the Epstein-Barr virus (EBV) gH/gL glycoprotein complex as potential EBV vaccines.