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BioWorld - Thursday, April 9, 2026
Home » Topics » Disease categories and therapies » Immune

Immune
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Respiratory syncytial virus vaccine adjuvant CAF-08 shows promise for use in infants

Aug. 19, 2022
To develop a safe and effective respiratory syncytial virus (RSV) vaccine for use in early life, Boston Children's Hospital scientists and their collaborators developed CAF-08, a liposomal formulation consisting of combined TLR7 (3M-052) and Mincle (trehalose-6,6-dibehenate [TDB]) agonists and the RSV pre-F antigen.
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Blue Water Vaccines evaluates VLP platform for monkeypox vaccine

Aug. 18, 2022
Blue Water Vaccines (BWV) will attempt to present monkeypox antigens within its norovirus shell and protrusion (S&P) virus-like particle (VLP) platform to develop a novel monkeypox vaccine.
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Codagenix receives DoD grant to advance CodaVax-DENV dengue vaccine

Aug. 17, 2022
The U.S. Department of Defense (DoD) is awarding Codagenix USD 4.4 million for further development of its next-generation tetravalent dengue vaccine candidate CodaVax-DENV.
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Intranasal SARS-CoV-2 vesicular stomatitis virus chimera vaccine immunogenic in animals

Aug. 16, 2022
International AIDS Vaccine Initiative (IAVI) and Merck & Co. scientists have developed a SARS-CoV-2 vaccine using the vesicular stomatitis virus (VSV) chimeric virus approach, wherein VSV was modified by substituting the VSV G surface glycoprotein gene with a coding sequence for the SARS-CoV-2 spike (S) glycoprotein.
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IC-100 downregulates inflammation through a unique mechanism of action

Aug. 10, 2022
Researchers from University of Miami Miller School of Medicine reported preclinical data for ZyVersa Therapeutics' novel humanized IgG4 monoclonal antibody targeting apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC), named IC-100.
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Replicating RNA vaccine protects mice from Crimean-Congo hemorrhagic fever

Aug. 10, 2022
Crimean-Congo hemorrhagic fever virus (CCHFV) causes a severe febrile illness with a mortality rate of up to 30%.
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Human anatomy

First physical wiring system for the human immune system

Aug. 8, 2022
By Nuala Moran
A first-of-its-kind comprehensive map of the network of connections in the human immune system has uncovered previously unknown interactions and filled in gaps in understanding why approved immunotherapies work in some patients and not others.
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First physical wiring system for the human immune system

Aug. 8, 2022
A first-of-its-kind comprehensive map of the network of connections in the human immune system has uncovered previously unknown interactions and filled in gaps in understanding why approved immunotherapies work in some patients and not others.
Read More

Layered nanoparticles containing stabilized HA broadly protect mice against influenza B strains

Aug. 8, 2022
Novel influenza vaccines with a broader protective spectrum are urgently needed to face viral seasonal variability and epidemic outbreaks.
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Epstein-Barr virus gH/gL nanoparticle vaccines demonstrate protection in vivo

Aug. 5, 2022
Scientists from the University of Washington and the Fred Hutchinson Cancer Research Center and their collaborators have described the generation of self-assembling nanoparticles displaying the Epstein-Barr virus (EBV) gH/gL glycoprotein complex as potential EBV vaccines.
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