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BioWorld - Monday, July 6, 2026
Home » Topics » Disease categories and therapies » Immune

Immune
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Immune

Primo Thera synthesizes new IL-6Rβ inhibitors

July 2, 2026
No Comments
Primo Thera Co. Ltd. has divulged new interleukin-6 receptor subunit β (IL-6Rβ; gp130) inhibitors potentially useful for the treatment of autoimmune disease.
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Nasal spray
Immune

Abera’s intranasal influenza vaccine shows promise in ferrets

July 2, 2026
No Comments
Abera Bioscience AB has completed a ferret study with its intranasal influenza vaccine candidate. The results were consistently strong and encourage the continued development of the program. Abera intends to publish detailed study data in a peer-reviewed scientific journal.
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Illustration of antibodies flying around a kidney

In 2nd deal of week, Ipsen buys Memo’s kidney transplant antibody

July 1, 2026
By Nuala Moran
No Comments
Ipsen SA announced its second acquisition of the week, saying it will pay €700 million (US$797 million) for Memo Therapeutics AG and its phase III-ready drug potravitug, a treatment for BK virus-associated infections and nephropathy in immune-compromised kidney transplant patients.
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Dollar symbol with arrow graph

Nuvectis shares continue to rally after $1.46B Haisco deal

June 30, 2026
By Marian (YoonJee) Chu
No Comments
Nuvectis Pharma Inc.’s shares climbed further after the oncology-focused biotech nabbed select rights to a late-stage complement factor B inhibitor (HSK-39297/NXP-100) and a phase I BRAF inhibitor (HSK-42360/NXP-200) from Haisco Pharmaceutical Group Co. Ltd. for $40 million up front.
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Photo of pen and marker on science journal article

NEJM paper on Tavneos pivotal trial retracted by academic authors

June 30, 2026
By Nuala Moran
No Comments
The academic authors of the paper describing the pivotal trial of Amgen Inc.’s Tavneos (avacopan) have retracted it from The New England Journal of Medicine because the primary endpoint assessments of nine patients were “re-adjudicated” after the database was locked and the study unblinded.
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Illustration demonstrating gut-brain axis
Neurology/psychiatric

CINP 2026: Gut microbiota could predict antidepressant response

June 30, 2026
By Mar de Miguel
No Comments
The gut microbiota may be altered in people with depression as a result of treatment. These microorganisms reorganize differently in individuals who respond to therapy. In a multiomics study of antidepressant-naive patients presented at the 2026 World Congress of Neuropsychopharmacology (CINP), scientists from National Taiwan University found that patients who improved after antidepressant treatment maintained a more balanced and functional microbial ecosystem, recovered beneficial metabolites, and displayed blood-based biological signals that aligned with these changes.
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Handshake, businessmen holding dollar sign, lightbulb
Immune

Deerfield-backed Boulevard, Metis pen $1.6B trispecific TCE deal

June 30, 2026
By Marian (YoonJee) Chu
No Comments
A U.S. biotechnology company founded by Deerfield Management Company L.P. licensed exclusive rights to Metis Techbio Co. Ltd.’s preclinical trispecific T-cell engager (TCE) for autoimmune disorders in a potential $1.62 billion deal.
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EU flags at European Commission building

EMA reverses its stance on Acadia’s Rett syndrome therapy Daybu

June 29, 2026
By Nuala Moran
No Comments
Following an initial rebuff in February 2026, the EMA’s Committee for Medicinal Products for Human Use (CHMP) is recommending approval of Acadia Pharmaceuticals Inc.’s Daybu (trofinetide) for treating neurobehavioral symptoms of Rett syndrome, after it took another look at the file.
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Illustration demonstrating gut-brain axis
Neurology/psychiatric

CINP 2026: Gut microbiota could predict antidepressant response

June 29, 2026
By Mar de Miguel
No Comments
The gut microbiota may be altered in people with depression as a result of treatment. These microorganisms reorganize differently in individuals who respond to therapy. In a multiomics study of antidepressant-naive patients presented at the 2026 World Congress of Neuropsychopharmacology (CINP), scientists from National Taiwan University found that patients who improved after antidepressant treatment maintained a more balanced and functional microbial ecosystem, recovered beneficial metabolites, and displayed blood-based biological signals that aligned with these changes.
Read More
Tavneos

EMA to pull Amgen’s Tavneos over ‘incorrect and misleading’ data

June 26, 2026
By Nuala Moran
No Comments
The EMA is recommending withdrawing Amgen Inc.’s complement inhibitor Tavneos (avacopan) from the market in Europe, saying data provided at the time it assessed the MAA “were found to be incorrect and misleading and could no longer be relied upon for demonstrating Tavneos’ effectiveness.”
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