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BioWorld - Tuesday, June 23, 2026
Home » Topics » Disease categories and therapies » Infection

Infection
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Infection

Arrepath describes new LpxH inhibitors

Nov. 24, 2025
Arrepath Inc. has identified UDP-2,3-diacylglucosamine hydrolase (LpxH) (bacterial) inhibitors reported to be useful for the treatment of gram-negative bacterial infections.
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Infection

Invivyd nominates VBY-329 as candidate for RSV prevention

Nov. 24, 2025
No Comments
Invivyd Inc. has nominated VBY-329 as a preclinical development candidate for the prevention of respiratory syncytial virus (RSV) among neonates, infants and children.
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AI-generated art for viral infection of the lungs
Infection

In lethal influenza, repair the lung before it’s too late

Nov. 24, 2025
By Coia Dulsat
No Comments
NIH researchers report that in severe influenza, survival improves at late stages only when antivirals are combined with therapies that repair lung damage or limit harmful T-cell responses, explaining why anti-inflammatory treatments alone are often ineffective.
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Scientist with vial
Immune

Evaxion reports antigen data from EVX-V1 CMV vaccine program

Nov. 21, 2025
No Comments
Evaxion A/S is advancing its cytomegalovirus (CMV) vaccine program, EVX-V1, with new data demonstrating protective effects of lead antigens in the program. EVX-V1 is a next-generation, multicomponent vaccine program combining novel AI-discovered antigens with AI-optimized versions of established CMV vaccine antigens.
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Infection

Zhuhai United Laboratories discovers new β-lactamase inhibitors

Nov. 19, 2025
Zhuhai United Laboratories Co. Ltd. has described β-lactamase (bacterial) inhibitors reported to be useful for the treatment of bacterial infections.
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Colorized transmission electron micrograph of yellow fever virus particles.
Infection

Mabloc and Instituto Butantan partner on MBL-YFV-01

Nov. 19, 2025
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Mabloc LLC has established a strategic partnership with Instituto Butantan to co-develop and manufacture MBL-YFV-01, a monoclonal antibody therapy for yellow fever virus (YFV) infection, including emergency post-exposure use.
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Microbiome illustration
Dental

‘Most complete’ map of oral microbiome enables links to systemic disease

Nov. 18, 2025
By Marian (YoonJee) Chu
No Comments
South Korean researchers led by Lee In-suk of Yonsei University have reported the most complete oral microbiome catalog to date, with more than 72,000 genomes. Detailed in Cell Host & Microbe on Nov. 12, 2025, the database is expected to serve as a universal platform for academia and enable “precision microbiome medicine” for the industry, Lee told BioWorld.
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Test tubes, dropper and capsules
Infection

Scynexis fungerps among funding recipients

Nov. 18, 2025
No Comments
Scynexis Inc. has announced that a novel series of antifungal compounds utilizing its proprietary triterpenoid antifungal platform are among five projects funded by a federal grant awarded to the new accelerator consortium led by researchers from Hackensack Meridian Center for Discovery and Innovation (CDI) and the Johns Hopkins Bloomberg School of Public Health.
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Gloved hand holding petri dish in lab
Infection

GSK and Fleming Initiative announce AMR research programs

Nov. 18, 2025
No Comments
GSK plc and the Fleming Initiative have announced six major new research programs to find new ways to slow the progress of antimicrobial resistance (AMR). The Fleming Initiative is a collaboration established by Imperial College London and Imperial College Healthcare NHS Trust to help tackle AMR. Each of the new programs will begin by early next year and are fully funded for 3 years.
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Infection

Synergistic antiviral efficacy of HEC-191834 with siRNA in HBV models

Nov. 18, 2025
No Comments
In preclinical studies at Sunshine Lake Pharma Co. Ltd., researchers investigated the antiviral and immune-modulatory potential of HEC-191834, a novel and highly selective human Toll-like receptor 8 (TLR8) agonist, in chronic hepatitis B virus (HBV) models, as well as its activity when combined with siRNA.
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