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BioWorld - Wednesday, December 10, 2025
Home » Topics » Disease categories and therapies » Infection

Infection
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Colorized transmission electron micrograph of an mpox virus particle
Infection

New recombinant strain of mpox virus identified in the UK

Dec. 10, 2025
By Nuala Moran
No Comments
The UK Health Security Agency (UKHSA) has identified a new recombinant strain of mpox (formerly monkeypox) that contains elements of clade Ib and clade IIb of the virus, in a traveler who recently returned from Asia. In a paper describing the new strain, the researchers at UKHSA say it is not possible to determine from a single genome how long the recombinant virus has been in circulation, or whether it will have a fitness benefit over currently circulating lineages.
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Infection

Centauri Therapeutics patents new peptide conjugates to treat infection

Dec. 10, 2025
Centauri Therapeutics Ltd. has disclosed conjugates consisting of a peptide such as polymyxin or its derivative covalently linked to a rhamnose unit via a linker reported to be useful for the treatment of infections.
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Gloved hands holding mRNA vaccine vial
Immune

Korean consortium to develop mRNA vaccine for SFTS virus

Dec. 10, 2025
No Comments
A consortium including Korea Disease Control and Prevention Agency (KDCA), International Vaccine Institute (IVI), ST Pharm Co. Ltd. and Seoul National University (SNU) is joining forces with CEPI to advance a new AI-designed mRNA vaccine to protect against tick-borne severe fever with thrombocytopenia syndrome (SFTS) virus, or Dabie bandavirus. CEPI is providing up to US$16 million to the project, led by IVI, to test the vaccine’s safety and ability to generate a suitable immune response in healthy adults in preclinical and phase I/II trials in Korea.
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Colorized transmission electron micrograph of an mpox virus particle

New recombinant strain of mpox virus identified in the UK

Dec. 9, 2025
By Nuala Moran
No Comments
The UK Health Security Agency has identified a new recombinant strain of mpox (formerly monkeypox) that contains elements of clade Ib and clade IIb of the virus, in a traveler who recently returned from Asia.
Read More
Nipah virus infection can cause acute respiratory syndrome and severe encephalitis
Infection

Anti-SARS-CoV-2 drug may also be effective against Nipah virus

Dec. 9, 2025
No Comments
The RNA-based Nipah virus, which causes acute respiratory illness and fatal encephalitis, can be transmitted from fruit bats to humans directly or indirectly via pigs or horses. Researchers at Wuhan Institute of Virology, Chinese Academy of Sciences and collaborators wondered whether their oral nucleoside prodrug VV-116, recently licensed against human coronaviruses such as SARS-CoV-2 in China, would be effective against Nipah virus.
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Mirum adds to rare live disease portfolio with $820M Bluejay buy

Dec. 8, 2025
No Comments
Mirum Pharmaceuticals Inc. is buying privately held Bluejay Therapeutics Inc., an $820 million purchase that will bring it Bluejay’s lead asset, brelovitug, for treating chronic hepatitis D virus.
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Vial and syringe with blue hues

Hippocratic loath? ‘Harm’ threat from ACIP’s proposed HBV shift

Dec. 5, 2025
By Randy Osborne
No Comments
Individual liberty and choice vs. wider public health became one predictable hinge upon which swung the often-acerbic debates at the CDC’s Advisory Committee for Immunization Practices (ACIP) meeting, which took up – again – the matter of hepatitis B virus (HBV) vaccine scheduling, a day after the panel voted not to vote on such guidance.
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Infant receiving vaccine

ACIP votes on changes to hep B immunization delayed once again

Dec. 4, 2025
By Mari Serebrov
No Comments
Disorganization resulting from last-minute changes to voting questions involving new recommendations for hepatitis B virus vaccines created a moment of déjà vu Dec. 4 when the CDC’s Advisory Committee for Immunization Practices (ACIP) voted 6-3 to once again delay its votes on whether the current recommended birth dose should be pushed back.
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Baby with bandage on thigh

Data-based concerns reveal consequence of hep B backsliding

Dec. 3, 2025
By Mari Serebrov
No Comments
“Do not take us backwards,” many doctors and other stakeholders implored the CDC’s Advisory Committee for Immunization Practices ahead of its meeting that starts Dec. 4 with a day-long discussion and votes on whether the current recommended birth dose of the hepatitis B virus vaccine should be delayed.
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Infection

Zhimeng Biopharma describes new compounds to treat HBV infection

Dec. 3, 2025
Zhimeng Biopharma has identified compounds reported to be useful for the treatment of hepatitis B viral (HBV) infection.
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