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BioWorld - Thursday, May 28, 2026
Home » Topics » Disease categories and therapies » Infection

Infection
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Close up of bow of cruise ship
Infection

Hantavirus is ‘sentinel’ more than acute pandemic threat

May 8, 2026
By Anette Breindl
No Comments
News of eight infections and three deaths so far due to an emerging zoonotic virus has brought back unhappy memories of the early days of SARS-CoV-2. At a press conference on Thursday, officials from the WHO did their best to calm the public’s fears that the MV Hondius, the ship currently heading to the Canary Islands with its remaining passengers plus assorted medical, WHO and European Center for Disease Prevention and Control staff, is the 2026 version of the Diamond Princess.
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Illustration of liver infection
Infection

Hepatitis A vaccine nonclinical efficacy can be tested in IFN receptor KO mice

May 8, 2026
No Comments
Conventional mouse models are not susceptible to hepatitis A virus (HAV) because murine adaptor protein MAVS is not efficiently cleaved by HAV protease precursors, so intact type I interferon (IFN) signaling blocks productive infection. However, IFN receptor knockout (KO) mice are susceptible to HAV infection and show hallmark features of the infection, having recently been identified as a potential disease model. Researchers from Genematrix Inc. aimed to determine whether nonclinical efficacy studies can be performed in small animal models.
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3D illustration of enveloped HIV
HIV/AIDS

Two-step HIV vaccine induces broadly neutralizing antibodies

May 8, 2026
By Mar de Miguel
No Comments
A designed chimeric virus induced broadly neutralizing antibodies (bNAbs) against the macaque equivalent of HIV. The strategy works in two steps: first it uses an envelope protein (Env) with a mutation that reduces the glycan shield that makes it invisible to the immune system, and then it exposes the part of the protein most likely to generate these antibodies capable of blocking many variants of the virus. The macaques developed potent and diverse antibodies with this approach, which pave the way for the development of an HIV-1 vaccine.
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Viruses
Index insights

Moderna, Vir among early 2026 top infectious disease gainers

May 7, 2026
By Amanda Lanier
No Comments
Infectious disease-focused biopharma stocks, tracked on the BioWorld Infectious Disease Index (BIDI), saw their collective shares roughly follow the path of broader markets like the Nasdaq Biotechnology Index (NBI) and the Dow Jones Industrial Average (DJIA) in early 2026. The BIDI ended April up 3.8%, followed by the DJIA with a 3.31% gain and 2.73% for the NBI, following a similar pattern to 2025.
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Rendering of a key measles protein targeted by neutralizing human antibodies
Infection

First measles treatment advances as vaccination rates drop

May 7, 2026
By Mar de Miguel
No Comments
Scientists at the La Jolla Institute for Immunology have identified and characterized human antibodies that neutralize the measles virus by blocking its entry into the cell. This is the first time that antibodies have been shown to bind effectively to two essential viral proteins, creating a dual blockade that prevents infection. Unlike the current vaccine, which is based on an attenuated virus and is not recommended for immunocompromised individuals, these monoclonal antibodies could be used both as a new vaccine approach and as a treatment for the entire population.
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Close up of bow of cruise ship

Hantavirus is ‘sentinel’ more than acute pandemic threat

May 7, 2026
By Anette Breindl
No Comments
News of eight infections and three deaths so far due to an emerging zoonotic virus has brought back unhappy memories of the early days of SARS-CoV-2. At a press conference on Thursday, officials from the WHO did their best to calm the public’s fears that the MV Hondius, the ship currently heading to the Canary Islands with its remaining passengers plus assorted medical, WHO and European Center for Disease Prevention and Control staff, is the 2026 version of the Diamond Princess.
Read More
Illustration of HIV showing trimers
HIV/AIDS

Liposomes displaying Env trimers drive HIV apex-focused responses

May 4, 2026
By Mar de Miguel
No Comments
A new vaccination strategy designed to induce antibodies that recognize the apex of the HIV Env protein uses Env trimers displayed on liposomes to increase their density and orient them correctly. This presentation enhanced apex-focused antibody responses in macaques, and the monoclonal antibodies isolated after immunization showed binding modes and structural features resembling human broadly neutralizing antibodies (bNAbs), indicating that the vaccine can steer the antibody response toward this vulnerable site.
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HHS appeals federal injunction ruling on vaccine changes

April 30, 2026
No Comments
The U.S. Department of Health and Human Services (HHS) has appealed a recent federal ruling that put on hold several changes to the childhood vaccine schedule and the Advisory Committee on Immunization Practices as reconstituted by HHS Secretary Robert Kennedy.
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Microscopic image of Group A streptococcus bacteria.
Infection

Aventera raises funding for streptococcal infection program

April 29, 2026
No Comments
Aventera Antibodies AB has successfully raised SEK14.5 million (US$15.6 million) in a funding round to support the preclinical development of the company’s lead drug candidate for life-threatening streptococcal infections.
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Criminal charges filed against top Fauci aide

April 28, 2026
No Comments
An alleged coverup of NIH-funded gain-of-function research at China’s Wuhan Institute of Virology has led to criminal charges against a former career scientist and top aide to Tony Fauci, the head of the National Institute of Allergy and Infectious Diseases in the time of the COVID-19 pandemic.
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