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BioWorld - Thursday, May 22, 2025
Home » Topics » Disease categories and therapies » Infection

Infection
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Antibodies binding to spike proteins on the surface of SARS-CoV-2 virus
Inflammatory

Australian researchers discover new compound to treat long COVID

April 15, 2025
By Tamra Sami
Researchers have developed a new compound that can prevent long COVID symptoms in mice that could lead to a future drug for the debilitating condition in humans. Developed by researchers at the Walter and Eliza Hall Institute of Medical Research (WEHI) in Melbourne, the world-first study found mice treated with the antiviral compound were protected from long-term brain and lung dysfunction, which are key symptoms of long COVID.
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Viruses

Pandemic potential is plentiful, but the next bug’s specifics are known unknown

April 15, 2025
By Anette Breindl
Compared to other forms of prevention, a unique issue for pandemic preparedness is that it is forever unclear what pathogen, exactly, the world needs to be prepared for. There are an estimated 300,000 viruses that infect mammals; add in birds, and the estimate grows to more than half a million. Some of those viruses are much greater threats than others.
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Antibodies binding to spike proteins on the surface of SARS-CoV-2 virus
Inflammatory

Australian researchers discover new compound to treat long COVID

April 15, 2025
By Tamra Sami
Researchers have developed a new compound that can prevent long COVID symptoms in mice that could lead to a future drug for the debilitating condition in humans. Developed by researchers at the Walter and Eliza Hall Institute of Medical Research (WEHI) in Melbourne, the world-first study found mice treated with the antiviral compound were protected from long-term brain and lung dysfunction, which are key symptoms of long COVID.
Read More
Infection

Mandimycin, a polyene macrolide with potent antifungal activity and distinctive mode of action

April 15, 2025
Writing in Nature, researchers from China Pharmaceutical University and Shandong University have revealed the discovery of a new polyene antifungal antibiotic, mandimycin.
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Infection

Coronavirus entry inhibitors disclosed in Yeda Research and Development patent

April 14, 2025
Yeda Research and Development Co. Ltd. has divulged broad-spectrum coronavirus entry inhibitors reported to be useful for the treatment of SARS-CoV-2 infection (COVID-19), SARS-CoV infection and Middle East respiratory syndrome coronavirus (MERS-CoV) infection.
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Illustration of Nipah virus
Immune

A single, intranasal dose of fast-acting adenoviral vaccines protects hamsters against highly lethal Nipah virus

April 14, 2025
Nipah virus, which circulates in fruit bats and other animals primarily in Asia and the South Pacific, causes severe neurological respiratory disease in humans and leads to death in 40%-75% of cases. The virus is endemic in Bangladesh and India, where outbreaks have occurred nearly annually since 2001.
Read More
Antibodies binding to spike proteins on the surface of SARS-CoV-2 virus
Inflammatory

Australian researchers discover new compound to treat long COVID

April 14, 2025
By Tamra Sami
Researchers have developed a new compound that can prevent long COVID symptoms in mice that could lead to a future drug for the debilitating condition in humans. Developed by researchers at the Walter and Eliza Hall Institute of Medical Research (WEHI) in Melbourne, the world-first study found mice treated with the antiviral compound were protected from long-term brain and lung dysfunction, which are key symptoms of long COVID.
Read More
Infection

New Mpro inhibitors revealed in Vir Biotechnology patent

April 10, 2025
Work at Vir Biotechnology Inc. has led to the identification of 3C-like proteinase (3CLpro; Mpro; nsp5) (SARS-CoV-2; COVID-19 virus) inhibitors reported to be useful for the treatment of SARS-CoV-2 infections (COVID-19).
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Influenza viruses with RNA, surface proteins hemagglutinin and neuraminidase
Immune

Orexo, Abera report proof-of-concept data for powder-based intranasal vaccine

April 10, 2025
Orexo AB has announced promising in vivo proof-of-concept data for a powder-based intranasal vaccine candidate based on Abera Bioscience AB’s BERA vaccine platform and formulated with Orexo’s Amorphox technology.
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Illustration of digital syringe
Immune

mRNA-based vaccine is immunogenic, protective in Lyme disease

April 10, 2025
Lyme disease is a multisystemic zoonotic infection caused by Borrelia burgdorferi bacteria transmitted by ticks. Lyme disease is a public health problem because of its high incidence in North America and Europe and its increasing presence due to the impacts of climate change on vector distribution. Novel, effective vaccines to prevent the disease are, therefore, urgently needed.
Read More
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