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BioWorld - Tuesday, December 23, 2025
Home » Topics » Disease categories and therapies » Infection

Infection
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Syringe in spotlight

Under new management, ACIP faces intense scrutiny

June 23, 2025
By Mari Serebrov
No Comments
The June 25-26 meeting of the U.S. CDC’s Advisory Committee for Immunization Practices (ACIP) will be anything but business as usual. In wiping the slate clean just two weeks before the panel was to meet, Health and Human Services Secretary Robert Kennedy made sure of that.
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Infection

Italian researchers patent Flavivirus inhibitors

June 23, 2025
CNCCS SCARL Collezione Nazionale Dei Composti Chimici E Centro Screening and IRBM SpA have prepared new serine protease NS3/non-structural protein 2B (NS3/NS2B) (dengue virus) and/or (West Nile virus) and/or (Zika virus) and/or Japanese encephalitis virus inhibitors.
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Vaccine vials and syringe
Immune

CEPI-backed consortium to develop all-in-one filovirus vaccine

June 23, 2025
No Comments
A global consortium led by Adaptvac ApS aims to design and test a new vaccine that could offer broad protection against several filoviruses, including Zaire ebolavirus, Sudan ebolavirus and Marburg virus.
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Xia Jin, CEO and co-founder of Immuno Cure, and Dan Mallon, senior vice president of corporate development for Pharmajet

Immuno Cure, Pharmjet partner on needle-free HIV vaccine trial

June 20, 2025
By Tamra Sami
No Comments
Immuno Cure Biotech Ltd. is collaborating with Pharmajet Inc. to evaluate the safety and immunogenicity of its HIV therapeutic DNA vaccine, Icvax, delivered via Pharmajet's innovative Tropis needle-free injection system.
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Illustration of HIV particles
HIV/AIDS

Combination of activated dendritic cells and anti-TIGIT immunotherapy to eliminate latent HIV reservoirs

June 20, 2025
No Comments
Researchers from Instituto de Investigación Sanitaria Hospital Universitario de La Princesa and collaborators have developed nanoparticles loaded with poly(I:C) and used them to prime monocyte-derived dendritic cells (Nano-PIC-MDDC), which in turn activate natural killer cells to eliminate HIV-infected CD4+ T cells.
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Immune

Bovine adenoviral vector-based bivalent vaccine protects mice and ferrets from influenza A and B

June 20, 2025
No Comments
Researchers from Purdue University and the U.S. Centers for Disease Control and Prevention have recently developed a novel influenza vaccine candidate that uses a bovine adenoviral (BAd) vector to deliver nucleoprotein (NP) antigens from both influenza A and B viruses, along with an autophagy-inducing peptide (C5) to enhance cellular immune responses, particularly T-cell responses.
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JAMA OpEd

Too much at stake for dismissed ACIP members to go quietly

June 18, 2025
By Mari Serebrov
No Comments
The 17 members abruptly terminated June 9 from the U.S. CDC’s Advisory Committee for Immunization Practices are not going gently into the night. Instead, they’re raging against what could be the dying of the light.
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Jyong’s $20M US IPO to help refile NDA of urological botanic drug

June 18, 2025
By Marian (YoonJee) Chu
No Comments
Jyong Biotech Ltd. raised $20 million from its Nasdaq debut June 17 to advance a pipeline of botanical drugs targeting male urinary disorders. The New Taipei City, Taiwan-headquartered company’s shares began trading under the ticker MENS, and closed at $10.11 apiece at the bell, up 34.80% from its listing price of $7.50 per share. Shares had kicked up to $15 at opening, reaching double its offering price.
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Infection

Assembly Biosciences describes new azetidine compounds for HSV infections

June 18, 2025

Assembly Biosciences Inc. has identified azetidine compounds reported to be useful for the treatment of herpes simplex virus (HSV) infections. 


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JAMA OpEd

Too much at stake for dismissed ACIP members to go quietly

June 17, 2025
By Mari Serebrov
No Comments
The 17 members abruptly terminated June 9 from the U.S. CDC’s Advisory Committee for Immunization Practices (ACIP) are not going gently into the night. Instead, they’re raging against what could be the dying of the light. The 17 raised their collective voices in a June 16 JAMA opinion piece to decry what’s at stake with Health and Human Services Secretary Robert Kennedy’s efforts, in his words, to “reestablish public confidence in vaccine science” by cleansing ACIP of what he claimed were conflicts due to members’ financial ties to industry.
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