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BioWorld - Wednesday, April 29, 2026
Home » Topics » Disease categories and therapies » Infection

Infection
Infection RSS Feed RSS

No postponement likely for ACIP meeting

June 24, 2025
By Mari Serebrov
No Comments
Barely a day before the eight new members of the U.S. CDC’s Advisory Committee for Immunization Practices (ACIP) are supposed to hold their first meeting, Sen. Bill Cassidy, R-La., called for the June 25 meeting to be postponed.
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Robert Paris, vice president, Moderna
Global Vaccine Forum 2025

Moderna expands mRNA tech to latent viruses, cancer, rare disease

June 24, 2025
By Marian (YoonJee) Chu
No Comments
Post pandemic, Moderna Inc. is broadening the applications of mRNA technology to cancer, rare diseases, latent viruses and respiratory viruses, “taking advantage” of the revenue generated by Spikevax (elasomeran), its mRNA-based vaccine for COVID-19.
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Senior man suffering from cold and flu

Cidara Navigates toward new flu option with phase IIb data

June 23, 2025
By Randy Osborne
No Comments
Cidara Therapeutics Inc. will meet with the FDA to discuss strongly favorable phase IIb results from its randomized, double-blind, placebo-controlled phase IIb Navigate trial testing CD-388 for the prevention of seasonal influenza in healthy, unvaccinated adults aged 18-64. Meanwhile, shares of the San Diego-based firm (NASDAQ:CDTX) closed June 23 at $44.95, up $23.93, or 113.8%, as Wall Street learned that the study met its primary endpoint, turning up a statistically significant prevention efficacy for each of three dose groups in people given a single shot at the beginning of the flu season.
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Syringe in spotlight

Under new management, ACIP faces intense scrutiny

June 23, 2025
By Mari Serebrov
No Comments
The June 25-26 meeting of the U.S. CDC’s Advisory Committee for Immunization Practices (ACIP) will be anything but business as usual. In wiping the slate clean just two weeks before the panel was to meet, Health and Human Services Secretary Robert Kennedy made sure of that.
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Infection

Italian researchers patent Flavivirus inhibitors

June 23, 2025
CNCCS SCARL Collezione Nazionale Dei Composti Chimici E Centro Screening and IRBM SpA have prepared new serine protease NS3/non-structural protein 2B (NS3/NS2B) (dengue virus) and/or (West Nile virus) and/or (Zika virus) and/or Japanese encephalitis virus inhibitors.
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Vaccine vials and syringe
Immune

CEPI-backed consortium to develop all-in-one filovirus vaccine

June 23, 2025
No Comments
A global consortium led by Adaptvac ApS aims to design and test a new vaccine that could offer broad protection against several filoviruses, including Zaire ebolavirus, Sudan ebolavirus and Marburg virus.
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Xia Jin, CEO and co-founder of Immuno Cure, and Dan Mallon, senior vice president of corporate development for Pharmajet

Immuno Cure, Pharmjet partner on needle-free HIV vaccine trial

June 20, 2025
By Tamra Sami
No Comments
Immuno Cure Biotech Ltd. is collaborating with Pharmajet Inc. to evaluate the safety and immunogenicity of its HIV therapeutic DNA vaccine, Icvax, delivered via Pharmajet's innovative Tropis needle-free injection system.
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Illustration of HIV particles
HIV/AIDS

Combination of activated dendritic cells and anti-TIGIT immunotherapy to eliminate latent HIV reservoirs

June 20, 2025
No Comments
Researchers from Instituto de Investigación Sanitaria Hospital Universitario de La Princesa and collaborators have developed nanoparticles loaded with poly(I:C) and used them to prime monocyte-derived dendritic cells (Nano-PIC-MDDC), which in turn activate natural killer cells to eliminate HIV-infected CD4+ T cells.
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Immune

Bovine adenoviral vector-based bivalent vaccine protects mice and ferrets from influenza A and B

June 20, 2025
No Comments
Researchers from Purdue University and the U.S. Centers for Disease Control and Prevention have recently developed a novel influenza vaccine candidate that uses a bovine adenoviral (BAd) vector to deliver nucleoprotein (NP) antigens from both influenza A and B viruses, along with an autophagy-inducing peptide (C5) to enhance cellular immune responses, particularly T-cell responses.
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JAMA OpEd

Too much at stake for dismissed ACIP members to go quietly

June 18, 2025
By Mari Serebrov
No Comments
The 17 members abruptly terminated June 9 from the U.S. CDC’s Advisory Committee for Immunization Practices are not going gently into the night. Instead, they’re raging against what could be the dying of the light.
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