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BioWorld - Thursday, April 16, 2026
Home » Topics » Disease categories and therapies » Infection

Infection
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Jury convicts biotech execs in fraud scheme

Dec. 11, 2024
By Mari Serebrov
Nearly three years after being terminated as president and CEO of Cytodyn Inc., Nader Pourhassan was convicted June 9 by a U.S. federal jury for his role in a securities fraud scheme to deceive investors about the Vancouver, Wash.-based company’s development of leronlimab. The jury also convicted Kazem Kazempour, the CEO of Amarex Clinical Research LLC, a contract research organization hired by Cytodyn, for his part in the scheme.
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Dollar sign droplet above test tube
Infection

Financing at Orthogon Therapeutics supports development of oral therapy for BK virus

Dec. 11, 2024
Orthogon Therapeutics LLC has closed an oversubscribed financing round, with funding to be used to accelerate the development of its first-in-class treatments for managing BK virus reactivation in transplant patients.
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Illustration of receptor binding site of the A/Texas/37/2024 hemagglutinin Leu226 mutant
Infection

A single mutation in H5N1 is all that’s needed for easier transmissibility

Dec. 10, 2024
By Mar de Miguel
Although it does not generally infect humans, a single mutation of the H5N1 virus in the highly pathogenic avian and bovine clade 2.3.4.4b could overcome this barrier and possibly trigger a pandemic.
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COVID-19 research illustration
Biomarkers

miR-1-3p levels predict case severity in hospitalized COVID-19 patients

Dec. 10, 2024

Increasing evidence shows that circulating microRNAs (miRNAs) regulate biological processes involved in COVID-19 complications.


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SARS-CoV-2 illustration turns from blue to red
Infection

Sunshine Biopharma’s PLpro inhibitor shows activity in SARS-CoV-2

Dec. 10, 2024
Sunshine Biopharma Inc. announced it has developed an orally active protease inhibitor that showed dose-dependent antiviral activity in mice infected with SARS-CoV-2.
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Illustration of female reproductive system with cancer tissue on the cervix
Cancer

Oncolytic virus SONC-103 has activity in HPV16+ cervical cancer

Dec. 10, 2024
Chinese researchers presented a novel recombinant oncolytic HSV-1, named SONC-103.
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Pediatric exam

Enanta logs phase II RSV win with zelicapavir

Dec. 9, 2024
By Randy Osborne
Enanta Pharmaceuticals Inc. hit the mark that Wall Street hoped for, and details rolled out in top-line results from the first-in-pediatrics phase II study evaluating once-daily, oral zelicapavir in hospitalized and non-hospitalized children aged 28 days to 36 months with respiratory syncytial virus (RSV).
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Lab mouse
HIV/AIDS

Humanized mouse model for evaluating SIV, HIV therapies

Dec. 9, 2024

In a recent publication, researchers from Colorado State University presented the development and evaluation of humanized mice as a hybrid dual-use model for testing therapeutics against both HIV and SIV infections.


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Illustration of receptor binding site of the A/Texas/37/2024 hemagglutinin Leu226 mutant
Infection

A single mutation in H5N1 is all that’s needed for easier transmissibility

Dec. 9, 2024
By Mar de Miguel
Although it does not generally infect humans, a single mutation of the H5N1 virus in the highly pathogenic avian and bovine clade 2.3.4.4b could overcome this barrier and possibly trigger a pandemic. Scientists at The Scripps Research Institute have warned of this possibility after studying the three-dimensional structure of the viral hemagglutinin and seeing how a change in one amino acid would make it more suitable for the human cell receptor. The researchers stress the need to monitor new mutations of this virus in order to act quickly in case the global jump to our species occurs.
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Renerve Nervalign
Newco News

Renerve raises AU$7M in Australian IPO for nerve repair

Dec. 5, 2024
By Tamra Sami
After raising AU$7 million (US$4.5 million) in is initial public offering on the Australian Securities Exchange last week, Renerve Ltd. is already exploring mainland China for its portfolio of nerve repair and regeneration products.
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