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Home » Topics » Disease categories and therapies » Inflammatory

Inflammatory
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Jun R. Huh at Healthcare Innovation Forum 2024

HIF 2024: Immune system could be key to neurodegenerative disease

Dec. 3, 2024
By Marian (YoonJee) Chu
Our immune cells are not just “defenders” against deadly viruses and pathogens but also a great balancer for tissue homeostasis. For neurological disorders, understanding the neuro-immune axis could be key to treating previously untreatable conditions such as autism spectrum disorder, according to Jun R. Huh, professor of immunology at Harvard Medical School.
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Immune

PAI-1 inhibitor MDI-2517 shows superior preclinical efficacy in systemic sclerosis models

Dec. 3, 2024
Researchers from the University of Michigan Medical School and MDI Therapeutics Inc. recently presented preclinical data for MDI-2517.
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Joint pain illustration
Inflammatory

Oral STAT3 inhibitor shows promising efficacy and safety profile in model of inflammatory arthritis

Dec. 2, 2024
Scientists from Recludix Pharma Inc. presented the preclinical characterization of REX-7117, an orally available, reversible, SH2 domain-targeting STAT3 inhibitor, being developed for the treatment of inflammatory diseases.
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Jun R. Huh at Healthcare Innovation Forum 2024

HIF 2024: Immune system could be key to neurodegenerative disease

Nov. 29, 2024
By Marian (YoonJee) Chu
Our immune cells are not just “defenders” against deadly viruses and pathogens but also a great balancer for tissue homeostasis. For neurological disorders, understanding the neuro-immune axis could be key to treating previously untreatable conditions such as autism spectrum disorder, according to Jun R. Huh, professor of immunology at Harvard Medical School.
Read More
Jun R. Huh at Healthcare Innovation Forum 2024

HIF 2024: Immune system could be key to neurodegenerative disease

Nov. 27, 2024
By Marian (YoonJee) Chu
Our immune cells are not just “defenders” against deadly viruses and pathogens but also a great balancer for tissue homeostasis. For neurological disorders, understanding the neuro-immune axis could be key to treating previously untreatable conditions such as autism spectrum disorder, according to Jun R. Huh, professor of immunology at Harvard Medical School.
Read More
Inflammatory

Nanjing Mingde New Drug Research describes new NLRP3 inflammasome inhibitors

Nov. 25, 2024
Nanjing Mingde New Drug Research Co. Ltd. has identified NLRP3 inflammasome inhibitors reported to be useful for the treatment of inflammation.
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Antibodies illustration
Inflammatory

Asahi Kasei Pharma licenses rights to Chiome’s humanized anti-CX3CR1 antibody

Nov. 22, 2024
Chiome Bioscience Inc. and Asahi Kasei Pharma Corp. have entered into an exclusive license agreement to develop and commercialize Chiome’s humanized anti-CX3CR1 antibody, PFKR, currently in the preclinical stage.
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Immune

Seed funding at Autoimmunity Biosolutions to advance immuno-corrective therapy for autoimmune diseases

Nov. 22, 2024
Autoimmunity Biosolutions has closed a seed financing to support its work advancing a next-generation, immuno-corrective therapy for autoimmune diseases. The company’s approach targets a branch of the interleukin-7 (IL-7)/interleukin-7 receptor (IL-7R) pathway controlled by the soluble IL-7R (sIL-7R), a critical amplifier of autoimmune reactions.
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Hidradenitis suppurativa illustration

UCB chalks hidradenitis suppurativa as fifth indication for Bimzelx

Nov. 20, 2024
By Randy Osborne
The U.S. FDA added hidradenitis suppurativa to the label for UCB SA’s Bimzelx (bimekizumab-bkzx), throwing renewed light on the indication, a chronic disease that causes painful, boil-like lumps that appear under the skin. Regulators cleared the humanized IL-17A and IL-17F antagonist for adults with moderate to severe HS, marking the drug’s fifth approval.
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Woman holding stomach with inflammation
Women's health

Holistic strategies needed to diagnose and treat endometriosis

Nov. 20, 2024
By Tamra Sami
Endometriosis has been woefully under-recognized in the medical community, and consequently, the delay between onset and diagnosis is often quite long, with some women waiting up to 12 years for a diagnosis. Endometriosis affects about 10% of women, and about 190 million women worldwide live with endometriosis.
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