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Home » Topics » Disease categories and therapies » Inflammatory

Inflammatory
Inflammatory RSS Feed RSS

Hidradenitis suppurativa illustration

UCB chalks hidradenitis suppurativa as fifth indication for Bimzelx

Nov. 20, 2024
By Randy Osborne
The U.S. FDA added hidradenitis suppurativa to the label for UCB SA’s Bimzelx (bimekizumab-bkzx), throwing renewed light on the indication, a chronic disease that causes painful, boil-like lumps that appear under the skin. Regulators cleared the humanized IL-17A and IL-17F antagonist for adults with moderate to severe HS, marking the drug’s fifth approval.
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Woman holding stomach with inflammation
Women's health

Holistic strategies needed to diagnose and treat endometriosis

Nov. 20, 2024
By Tamra Sami
Endometriosis has been woefully under-recognized in the medical community, and consequently, the delay between onset and diagnosis is often quite long, with some women waiting up to 12 years for a diagnosis. Endometriosis affects about 10% of women, and about 190 million women worldwide live with endometriosis.
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Chains of arrows going in opposite directions

Vitalli terminates $477M Daewoong deal, retains $941M option

Nov. 19, 2024
By Marian (YoonJee) Chu
Vitalli Bio Inc. terminated a potential $477 million licensing deal for autoimmune disease drug, DWP-213388, signed a year ago with Daewoong Pharmaceutical Co. Ltd., although Vitalli still retains option rights to two more dual inhibitor candidates that could fetch up to $941 million.
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White tablets spilling out of white bottle, blue background

Protagonist, J&J’s oral IL-23 psoriasis data strong (but short)

Nov. 19, 2024
By Karen Carey
IL-23 receptor antagonist icotrokinra hit co-primary phase III endpoints in moderate to severe plaque psoriasis, positioning the oral peptide at the forefront of a multibillion-dollar franchise for partners Protagonist Therapeutics Inc. and Johnson and Johnson.
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Woman holding stomach with inflammation
Healing the health divide

Holistic strategies needed to diagnose and treat endometriosis

Nov. 19, 2024
By Tamra Sami
Endometriosis has been woefully under-recognized in the medical community, and consequently, the delay between onset and diagnosis is often quite long, with some women waiting up to 12 years for a diagnosis.
Read More
Rocket launch illustration
Inflammatory

Slingshot Therapeutics launches to take forward programs from academia

Nov. 18, 2024
Slingshot Therapeutics Ltd. has launched with the aim of identifying and advancing therapeutic programs from academic institutions.
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Chains of arrows going in opposite directions

Vitalli terminates $477M Daewoong deal, retains $941M option

Nov. 15, 2024
By Marian (YoonJee) Chu
Vitalli Bio Inc. terminated a potential $477 million licensing deal for autoimmune disease drug, DWP-213388, signed a year ago with Daewoong Pharmaceutical Co. Ltd., although Vitalli still retains option rights to two more dual inhibitor candidates that could fetch up to $941 million.
Read More
Art concept for drug research
Inflammatory

Series B financing at Trex Bio supports immunology pipeline development

Nov. 14, 2024
Trex Bio Inc. has closed an oversubscribed $84 million series B financing round to support development of its pipeline of novel therapies that modulate the immune system to restore human tissue immune homeostasis.
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Dermatologic

Enveda advances ENV-294 into clinic for atopic dermatitis

Nov. 14, 2024
Enveda Therapeutics Inc. has received U.S. IND clearance and advanced into phase I trials with ENV-294, its naturally derived anti-inflammatory.
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Inflammatory

New ROCK2 inhibitors disclosed in Genosco patent

Nov. 13, 2024
Genosco Inc. has divulged Rho-associated protein kinase 2 (ROCK2) inhibitors reported to be useful for the treatment of fibrosis, cancer, cardiovascular and inflammatory disorders.
Read More
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