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Home » Topics » Disease categories and therapies » Inflammatory

Inflammatory
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Concept of business partnership

Relation inks two GSK deals tackling osteoarthritis, fibrotic disease

Dec. 12, 2024
By Nuala Moran
Relation Therapeutics Ltd. has delivered the first commercial validation of its combined wet lab/in silico platform for homing in on disease-related genes in the thick of the genome, signing two collaboration agreements with GSK plc, with a potential value of $200 million per target.
Read More
Man measuring waist

Caliway’s CBL-514 meets endpoints in reducing abdominal fat

Dec. 12, 2024
By Tamra Sami
Caliway Biopharmaceuticals’ lipolysis candidate, CBL-514, met all the primary and secondary efficacy endpoints in a phase IIb study for subcutaneous fat reduction, paving the way for the company to begin a global pivotal phase III study in 2025.
Read More
Ear illustration

Loud and clear: Sound Pharma has phase III success in Meniere’s

Dec. 11, 2024
By Lee Landenberger
Sound Pharmaceuticals Inc.’s lead candidate, the anti-inflammatory SPI-1005 (ebselen), has produced positive pivotal phase III study data in treating Meniere’s disease, an inner-ear disorder that can lead to vertigo and deafness.
Read More
Concept of business partnership
Inflammatory

Relation inks two GSK deals tackling osteoarthritis, fibrotic disease

Dec. 11, 2024
By Nuala Moran
Relation Therapeutics Ltd. has delivered the first commercial validation of its combined wet lab/in silico platform for homing in on disease-related genes in the thick of the genome, signing two collaboration agreements with GSK plc, with a potential value of $200 million per target.
Read More

Paradigm's AU$16M moves Zilosul to pivotal osteoarthritis trials

Dec. 10, 2024
By Tamra Sami
Paradigm Biopharmaceuticals Ltd. raised AU$16 million (US$10.31 million) in a placement that will allow the company to start a global phase III trial with its lead product, Zilosul (injectable pentosan polysulfate/iPPS), to treat osteoarthritis.
Read More
Concept of business partnership

Relation inks two GSK deals tackling osteoarthritis, fibrotic disease

Dec. 10, 2024
By Nuala Moran
Relation Therapeutics Ltd. has delivered the first commercial validation of its combined wet lab/in silico platform for homing in on disease-related genes in the thick of the genome, signing two collaboration agreements with GSK plc, with a potential value of $200 million per target.
Read More

Paradigm's AU$16M moves Zilosul to pivotal osteoarthritis trials

Dec. 9, 2024
By Tamra Sami
Paradigm Biopharmaceuticals Ltd. raised AU$16 million (US$10.31 million) in a placement that will allow the company to start a global phase III trial with its lead product, Zilosul (injectable pentosan polysulfate/iPPS), to treat osteoarthritis.
Read More

Citryll raises €85M series B to advance CIT-013 into phase II

Dec. 9, 2024
By Nuala Moran
Citryll BV has closed an €85 million (US$89.8 million) series B, enabling it to take CIT-013, an antibody designed to block pathological neutrophil extracellular traps that drive a wide range of immune-mediated inflammatory diseases, into phase IIa development.
Read More
Inflammatory

New STAT3 degradation inducers disclosed in Recludix patent

Dec. 9, 2024
Recludix Pharma Inc. has divulged proteolysis targeting chimeras (PROTACs) comprising cereblon (CRBN) ligands coupled to a signal transducer and activator of transcription 3 (STAT3) targeting moiety via a linker acting as STAT3 degradation inducers reported to be useful for the treatment of cancer and inflammatory disorders.
Read More
Jun R. Huh at Healthcare Innovation Forum 2024
HIF 2024

Immune system could be key to neurodegenerative disease

Dec. 5, 2024
By Marian (YoonJee) Chu
Our immune cells are not just “defenders” against deadly viruses and pathogens but also a great balancer for tissue homeostasis.
Read More
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