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Home » Topics » Disease categories and therapies » Inflammatory

Inflammatory
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Jun R. Huh at Healthcare Innovation Forum 2024
HIF 2024

Immune system could be key to neurodegenerative disease

Dec. 5, 2024
By Marian (YoonJee) Chu
Our immune cells are not just “defenders” against deadly viruses and pathogens but also a great balancer for tissue homeostasis.
Read More
Inflammatory

PROTACs targeting IRAK-4 described in Celgene patents

Dec. 5, 2024
Several recent Celgene Corp. patents detail the development of proteolysis targeting chimera (PROTAC) compounds comprising a cereblon (CRBN)-binding moiety covalently linked to an interleukin-1 receptor-associated kinase 4 (IRAK-4)-targeting moiety via a linker.
Read More
Immune

Kronos Bio’s KB-7898 reduces pathological scores in inflammatory disorders

Dec. 4, 2024
Kronos Bio Inc. has presented data on KB-7898, an orally available p300 KAT inhibitor.
Read More
Jun R. Huh at Healthcare Innovation Forum 2024

HIF 2024: Immune system could be key to neurodegenerative disease

Dec. 3, 2024
By Marian (YoonJee) Chu
Our immune cells are not just “defenders” against deadly viruses and pathogens but also a great balancer for tissue homeostasis. For neurological disorders, understanding the neuro-immune axis could be key to treating previously untreatable conditions such as autism spectrum disorder, according to Jun R. Huh, professor of immunology at Harvard Medical School.
Read More
Immune

PAI-1 inhibitor MDI-2517 shows superior preclinical efficacy in systemic sclerosis models

Dec. 3, 2024
Researchers from the University of Michigan Medical School and MDI Therapeutics Inc. recently presented preclinical data for MDI-2517.
Read More
Joint pain illustration
Inflammatory

Oral STAT3 inhibitor shows promising efficacy and safety profile in model of inflammatory arthritis

Dec. 2, 2024
Scientists from Recludix Pharma Inc. presented the preclinical characterization of REX-7117, an orally available, reversible, SH2 domain-targeting STAT3 inhibitor, being developed for the treatment of inflammatory diseases.
Read More
Jun R. Huh at Healthcare Innovation Forum 2024

HIF 2024: Immune system could be key to neurodegenerative disease

Nov. 29, 2024
By Marian (YoonJee) Chu
Our immune cells are not just “defenders” against deadly viruses and pathogens but also a great balancer for tissue homeostasis. For neurological disorders, understanding the neuro-immune axis could be key to treating previously untreatable conditions such as autism spectrum disorder, according to Jun R. Huh, professor of immunology at Harvard Medical School.
Read More
Jun R. Huh at Healthcare Innovation Forum 2024

HIF 2024: Immune system could be key to neurodegenerative disease

Nov. 27, 2024
By Marian (YoonJee) Chu
Our immune cells are not just “defenders” against deadly viruses and pathogens but also a great balancer for tissue homeostasis. For neurological disorders, understanding the neuro-immune axis could be key to treating previously untreatable conditions such as autism spectrum disorder, according to Jun R. Huh, professor of immunology at Harvard Medical School.
Read More
Inflammatory

Nanjing Mingde New Drug Research describes new NLRP3 inflammasome inhibitors

Nov. 25, 2024
Nanjing Mingde New Drug Research Co. Ltd. has identified NLRP3 inflammasome inhibitors reported to be useful for the treatment of inflammation.
Read More
Antibodies illustration
Inflammatory

Asahi Kasei Pharma licenses rights to Chiome’s humanized anti-CX3CR1 antibody

Nov. 22, 2024
Chiome Bioscience Inc. and Asahi Kasei Pharma Corp. have entered into an exclusive license agreement to develop and commercialize Chiome’s humanized anti-CX3CR1 antibody, PFKR, currently in the preclinical stage.
Read More
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