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BioWorld - Thursday, December 25, 2025
Home » Topics » Disease categories and therapies » Inflammatory

Inflammatory
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Gilead-Galapagos RA drug filgotinib rejected by FDA

Aug. 19, 2020
By Michael Fitzhugh and Lee Landenberger
An FDA rejection of Galapagos NV's rheumatoid arthritis (RA) drug filgotinib, announced Aug. 18, was "disappointing and unexpected," CEO Onno van de Stolpe said, adding that "there is so much more" to his company's story and pipeline. Gilead Sciences Inc., the Belgian company's partner and a substantial backer of both the drug and the pipeline, said it would "evaluate the points raised" by the CRL, but continued to believe in the drug.
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Gaining insights into loss of function

Aug. 18, 2020

Unity shares untied as osteoarthritis of the knee drug fails phase II test

Aug. 17, 2020
By Michael Fitzhugh
Shares of Unity Biotechnology Inc. (NASDAQ:UBX) fell 66.6% to $4.15 on Aug. 17 after UBX-0101, its one-time lead candidate, failed to best a placebo on an established measure of osteoarthritis pain in a phase II study.
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Daiichi Sankyo describes new SIRT6 activators

Aug. 13, 2020

New NLRP3 inflammasome inhibitors discovered at NodThera

Aug. 12, 2020

Daiichi Sankyo patents new SIRT6 activators

Aug. 7, 2020

Honest placebos change brain potentials

Aug. 4, 2020

Kyorin Pharmaceutical discloses new 15-hydroxyprostaglandin dehydrogenase inhibitors

July 30, 2020

Suzhou Zelgen Biosciences identifies new MAP3K5 inhibitors

July 29, 2020

Huihan Medical Technologies discloses new Wnt signaling inhibitors

July 14, 2020
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