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BioWorld - Wednesday, January 7, 2026
Home » Topics » Disease categories and therapies » Inflammatory

Inflammatory
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New NLRP3 inflammasome inhibitors discovered at NodThera

Aug. 12, 2020

Daiichi Sankyo patents new SIRT6 activators

Aug. 7, 2020

Honest placebos change brain potentials

Aug. 4, 2020

Kyorin Pharmaceutical discloses new 15-hydroxyprostaglandin dehydrogenase inhibitors

July 30, 2020

Suzhou Zelgen Biosciences identifies new MAP3K5 inhibitors

July 29, 2020

Huihan Medical Technologies discloses new Wnt signaling inhibitors

July 14, 2020

Sanofi expands protein degrader ambitions with $2.15B Kymera deal

July 13, 2020
By Michael Fitzhugh

The industry's expanding quest for protein degraders grew a little larger on July 9 with Sanofi SA tapping Kymera Therapeutics Inc. to advance two new protein degrader programs, one of which will target IRAK4 in patients with immune-inflammatory diseases and another for an undisclosed target. Each program could yield multiple therapies.


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Patric Stenberg and Roger Franklin

Gesynta raises $21M to test novel mechanism in systemic sclerosis

July 8, 2020
By Cormac Sheridan
DUBLIN – Gesynta Pharma AB raised SEK190 million (US$20.6 million) in new funding to move GS-248, a selective inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1), into a phase IIa trial in systemic sclerosis. The study is due to get underway toward the year end. “It’s going to be in the second half of the fourth quarter,” said Patric Stenberg, CEO of Lund, Sweden-based Gesynta.
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New galectin-3 inhibitors discovered at Bristol-Myers Squibb

July 1, 2020
Australian flag marking country on globe

Australia’s Cynata ahead of the pack as it progresses iPSCs to phase III osteoarthritis trial

June 30, 2020
By Tamra Sami
PERTH, Australia – Melbourne-based regenerative medicine company Cynata Therapeutics Ltd. is gearing up to take its Cymerus mesenchymal stem cell (MSC) product candidate, CYP-004, into a phase III trial in osteoarthritis.
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