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BioWorld - Thursday, April 16, 2026
Home » Topics » Disease categories and therapies » Musculoskeletal

Musculoskeletal
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First-in-human trial of the PET ligand [68Ga]DOTA-Siglec-9 targeting vascular adhesion protein 1

May 27, 2021

NanoCarrier describes shRNA/siRNA targeting mutant COL3A1

May 26, 2021

Bristol Myers Squibb identifies new TLR7/8/9 antagonists

May 25, 2021

Roche patents TLR antagonists

May 20, 2021

First-in-class small molecule PX-69 activates PLXDC2 to treat rheumatoid arthritis

May 20, 2021

Don’t walk away, Reneo poised to take flight in PPAR delta; Astellas too?

May 19, 2021
By Randy Osborne
Reneo Pharmaceuticals Inc.’s $93.8 million IPO last month brought renewed attention to primary mitochondrial myopathy (PMM), a genetic disorder that impairs oxidative phosphorylation, affecting mainly muscles. The San Diego-based firm sold about 6.2 million shares at $15 each, but the stock (NASDAQ:RPHM) has since taken a dive, closing May 19 at $8.83.
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T-cell modulation elicits long-term arthritis remission

May 19, 2021

Data presented from low-dose cohort of first-in-human trial FX-201

May 18, 2021

Interim phase I data for scAAV-2.5-IL1R as local gene therapy in OA of the knee

May 18, 2021
Skeletal system

Australian researchers map out first genetic profile of skeletal master regulator cells

May 17, 2021
By Tamra Sami
Researchers at Australia's Garvan Institute of Medical Research have for the first time mapped the genetic profile of the skeleton's master regulator cells, known as osteocytes.
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