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BioWorld - Sunday, April 12, 2026
Home » Topics » Disease categories and therapies » Musculoskeletal

Musculoskeletal
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Astellas stops dosing gene therapy for rare neuromuscular disease after trial's fourth SAE

Sep. 7, 2021
By Michael Fitzhugh
Astellas Pharma Inc. has halted further dosing of the experimental X-linked myotubular myopathy (XLMTM) gene therapy AT-132 (resamirigene bilparvovec) after one participant in the ongoing Aspiro study experienced a serious adverse event (SAE) of abnormal liver function.
Read More

IRF5 inhibition suppresses lupus-like disease in mice

Sep. 6, 2021

Glucocorticoid receptor agonist ADCs patented by AbbVie

Sep. 6, 2021

Astellas stops dosing gene therapy for rare neuromuscular disease after trial's fourth SAE

Sep. 1, 2021
By Michael Fitzhugh
Astellas Pharma Inc. has halted further dosing of the experimental X-linked myotubular myopathy (XLMTM) gene therapy AT-132 (resamirigene bilparvovec) after one participant in the ongoing Aspiro study experienced a serious adverse event (SAE) of abnormal liver function.
Read More

Eternity Bioscience patents new ADAMTS inhibitors

Sep. 1, 2021

Phase II trial of izokibep in ankylosing spondylitis commences dosing

Aug. 26, 2021

Clinical hold extended for ORTHO-R phase I/II study

Aug. 23, 2021

Shenzhen Salubris Pharmaceuticals presents new cathepsin K inhibitors

Aug. 13, 2021

Topline phase II data with Sarconeos in sarcopenia

Aug. 2, 2021

New glucocorticoid receptor modulators identified at Medshine Discovery

Aug. 2, 2021
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