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BioWorld - Saturday, March 14, 2026
Home » Topics » Disease categories and therapies » Neurology/psychiatric

Neurology/psychiatric
Neurology/psychiatric RSS Feed RSS

Drug capsule spilling onto brain

Angelini signs $550M deal for Sovargen’s ASO drug in epilepsy

Oct. 29, 2025
By Marian (YoonJee) Chu
No Comments
Sovargen Co. Ltd. inked a $550 million license deal with Angelini Pharma SpA, granting Angelini development and commercialization rights to SVG-105, a novel antisense oligonucleotide drug candidate in preclinical development as a potential treatment for intractable epilepsy.
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Ischemic stroke

Argenica’s stroke drug shows positive trends in functional outcomes

Oct. 28, 2025
By Tamra Sami
No Comments
Although Argenica Therapeutics Ltd.’s stroke drug, ARG-007, saw mixed results in top-line phase II data, new data in functional outcomes studies showed signs the drug helped patients think more clearly, regain independence, and enjoy a better quality of life after stroke.
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Chris Lai, cofounder and CEO, Metis at Nanoforge launch

Metis plans China NDA submission for orally dissolving PBA drug

Oct. 28, 2025
By Marian (YoonJee) Chu
No Comments
Based on positive phase III study results, Metis Techbio is planning to file an NDA for its AI-derived orally disintegrating tablet drug candidate for pseudobulbar affect, MTS-004, in China next year.
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IPO money

Muscarinic path still charting as Maplight IPO gets $258M

Oct. 28, 2025
By Randy Osborne
No Comments
Maplight Therapeutics Inc.’s pricing of a $258.9 million financing this week revived the debate over whether targeting the M1 as well as the M4 muscarinic receptor – as Bristol Myers Squibb Co. does with U.S. FDA-approved Cobenfy (xanomeline and trospium chloride) for schizophrenia – is a better strategy than going after M4 alone.
Read More
Chris Lai, cofounder and CEO, Metis at Nanoforge launch

Metis plans China NDA submission for orally dissolving PBA drug

Oct. 27, 2025
By Marian (YoonJee) Chu
No Comments
Based on positive phase III study results, Metis Techbio is planning to file an NDA for its AI-derived orally disintegrating tablet drug candidate for pseudobulbar affect, MTS-004, in China next year.
Read More
Ischemic stroke

Argenica’s stroke drug shows positive trends in functional outcomes

Oct. 27, 2025
By Tamra Sami
No Comments
Although Argenica Therapeutics Ltd.’s stroke drug, ARG-007, saw mixed results in top-line phase II data, new data in functional outcomes studies showed signs the drug helped patients think more clearly, regain independence, and enjoy a better quality of life after stroke.
Read More

Nex-z less sexy with second liver case; Intellia phase III paused

Oct. 27, 2025
By Randy Osborne
No Comments
Intellia Therapeutics Inc. followed up troubling news in May with a similar, and worse, update regarding the Magnitude and Magnitude-2 phase III trials with nexiguran ziclumeran, also known as nex-z, for patients with transthyretin amyloidosis with cardiomyopathy and polyneuropathy, respectively.
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Neurology/psychiatric

Korean scientists describe new KDM4C inhibitors

Oct. 27, 2025
Researchers at Dankook University and Korea University Research & Business Foundation Sejong Campus have identified thiophene derivatives acting as lysine-specific demethylase 4C (KDM4C; GASC-1; JMJD2C) inhibitors reported to be useful for the treatment of Alzheimer’s disease.
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Neurology/psychiatric

Bial-Portela divulges new OX2 receptor agonists

Oct. 27, 2025
Bial-Portela & Ca SA has synthesized orexin OX2 receptor agonists reported to be useful for the treatment of type 1 narcolepsy.
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Symbyx system

Symbyx light therapy shows sustained benefits in Parkinson’s

Oct. 24, 2025
By Tamra Sami
The largest study ever conducted on light therapy for Parkinson’s disease has found that long-term use of Symbyx Biome Pty Ltd.’s non-invasive, at-home photobiomodulation (PBM) devices significantly improved mobility, anxiety, and overall symptom severity.
Read More
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