Oncobix has discovered Bruton tyrosine kinase (BTK) inhibitors reported to be useful for the treatment of multiple sclerosis, inflammation, urticaria, systemic lupus erythematosus, allergy, rheumatoid arthritis, asthma and leukemia.

Sequence analysis of 131 human brains has revealed the mutagenesis processes that take place throughout life, from development to senescence. In a new study published in the July 29, 2022, issue of Science, the authors described how high rates of brain somatic mutations (what they call hypermutability) correlated with age. Their work includes certain neuropsychiatric diseases, where they found some genetic signatures that could be used for an early clinical diagnosis of different pathologies.

Japan’s Kyowa Kirin Co. Ltd. has stopped development of its adenosine A2a receptor antagonist, KW-6356, in Parkinson’s disease.