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BioWorld - Friday, April 17, 2026
Home » Topics » Disease categories and therapies » Neurology/psychiatric

Neurology/psychiatric
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Patent: “Methods and systems for detecting stroke.”

Point-of-care brain monitoring algorithm for detecting stroke in children

March 14, 2024
By Simon Kerton
In what represents their first patenting, a researcher from the University of California is seeking protection for non-invasive methods of brain monitoring that use electroencephalography (EEG) to detect new or worsening brain injury in pediatric patients.
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Neurology/Psychiatric

Xgene gains Australian clearance for phase I study of XG-2002

March 14, 2024
Xgene Pharmaceutical Pty Ltd., a subsidiary of Xgene Pharmaceutical Co. Ltd., has received approval in Australia to initiate a phase I trial of the selective TRPM8 blocker XG-2002 (RQ-00434739).
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Neurology/Psychiatric

New RIPK1 inhibitors patented by Genzyme

March 14, 2024
Genzyme Corp. (dba Sanofi Genzyme) has disclosed isoxazolidine compounds acting as receptor-interacting serine/threonine-protein kinase 1 (RIPK1; RIP-1) inhibitors reported to be useful for the treatment of Alzheimer’s disease and multiple sclerosis, among others.
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Mitochondria illustration
Neurology/Psychiatric

ASHA-091 restores mitochondrial function in models of neurodegeneration

March 14, 2024
Alterations in mitochondrial dynamics are hallmarks of Parkinson’s disease (PD) and other neurodegenerative disorders such as Alzheimer’s disease (AD).
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Drug Design, Drug Delivery & Technologies

Sangamo reports primate data with neurotropic AAV capsid variant STAC-BBB

March 14, 2024
Sangamo Therapeutics Inc. has reported data from nonhuman primate (NHP) studies showing the potential of its proprietary AAV capsid variant, STAC-BBB, as a neurotropic capsid when administered intravenously at clinically relevant doses. STAC-BBB outperformed results for other evaluated neurotropic capsid variants.
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Brain as light bulb filament
Neurology/Psychiatric

At AD/PD 2024, a look at how things go right

March 14, 2024
By Coia Dulsat
Advances in understanding the processes underlying brain neurodegeneration have allowed lots of new treatment and prevention strategies to begin to flourish. Several presentations at the 2024 Alzheimer’s & Parkinson’s Diseases Conference recently held in Lisbon reflect that eyes are now on some individuals who, despite showing pathological signs in their brains, stay cognitively healthy across several endogenous mechanisms of resilience.
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Peace of Mind Angle Touch device

Research to study new AT-04 pain relief device for endometriosis

March 13, 2024
By Marian (YoonJee) Chu
Japanese researchers from Chiba University are spearheading new research into Peace of Mind Co. Ltd.’s portable Angel Touch device (AT-04), approved for neurological disorders, to treat endometriosis-related pain.
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Neurology/Psychiatric

Agenebio describes new GABRA5 positive allosteric modulators

March 13, 2024
Agenebio Inc. has identified benzodiazepine derivatives acting as GABA(A) receptor subunits α5β3γ2 (GABRA5) positive allosteric modulators reported to be useful for the treatment of mild cognitive impairment, amyotrophic lateral sclerosis, schizophrenia, post-traumatic stress, autism, substance abuse and dependence, Alzheimer’s disease and Parkinson’s disease, among others.
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Man piecing together a puzzle
Neurology/Psychiatric

Pharmacological miR-155 blockade restricts neurodegenerative pathology and preserves cognitive function in AD

March 13, 2024
In a new study, researchers from Harvard Medical School and Regulus Therapeutics Inc. further investigated the role of miR-155 in Alzheimer's disease (AD).
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Brain with puzzle piece removed
Neurology/Psychiatric

ACI-19764 is a potent brain-penetrant NLRP3 inhibitor for neurological disorders

March 13, 2024
The activation of the NLRP3 inflammasome exacerbates neuronal dysfunction in several neurological diseases such as Alzheimer’s and Parkinson’s diseases, as well as multiple sclerosis. Targeting NLRP3 is an approach to overcome brain inflammation, among others.
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