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BioWorld - Wednesday, April 8, 2026
Home » Topics » Disease categories and therapies » Obesity

Obesity
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Liver disease

Mursla Bio partners with big pharma company on precision medicine

Nov. 25, 2025
By Shani Alexander
Mursla Bio Ltd. recently entered a partnership with an unnamed large pharmaceutical company to use its AI Precision Medicine platform to help with drug development and ultimately develop companion diagnostics. The collaboration uses Mursla’s platform ability to isolate and analyze extracellular vesicles from a simple blood sample, to provide biologically labelled, multiomics data to improve patient stratification, monitor treatment and develop companion diagnostics.
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South Korean won

Cha Group to Acquire Majority Stake in Kakao Healthcare

Nov. 25, 2025
By Marian (YoonJee) Chu
Kakao Healthcare Corp. plans to secure ₩100 billion (US$68 million) through two investment deals with Cha Biomedical Group and outside investors by early next year. The transactions, expected to close by the first quarter of 2026, will make Cha the controlling shareholder of Kakao Healthcare with a 43.08% stake. Kakao Corp., the parent company, will hold 29.99%, and external investors will own 26.93%.
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RNA strand

Lilly moves deeper into RNAi with $1.2B Sanegene obesity deal

Nov. 11, 2025
By Tamra Sami
No Comments
In a deal worth $1.2 billion, Suzhou Sanegene Bio Inc. and Eli Lilly and Co. are partnering to advance RNAi candidates for metabolic diseases based on Sanegene's tissue selective delivery technology.
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RNA strand

Lilly moves deeper into RNAi with $1.2B Sanegene obesity deal

Nov. 10, 2025
By Tamra Sami
No Comments
In a deal worth $1.2 billion, Suzhou Sanegene Bio Inc. and Eli Lilly and Co. are partnering to advance RNAi candidates for metabolic diseases based on Sanegene's tissue selective delivery technology.
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Pfizer Inc. signage

Pfizer, Metsera reach $10B merger agreement as Novo bows out

Nov. 10, 2025
By Jennifer Boggs
No Comments
Pfizer Inc. emerged over the weekend as the winner of the bidding war for Metsera Inc., with the two reaching an amended agreement after market close Nov. 7 that values the obesity drugmaker at about $10 billion. The next day, the other contender, Novo Nordisk A/S, confirmed it does not intend to increase its most recent offer.
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Lilly's amylin drug heads to phase III on strong weight loss data

Nov. 6, 2025
By Karen Carey
No Comments
Eli Lilly and Co.’s amylin receptor agonist, eloralintide, showed impressive weight loss and improved tolerability in phase II results reported at ObesityWeek 2025, setting the stage for a phase III trial to start next month. The once-weekly drug demonstrated superior mean weight reductions from 9.5% to 20.1% vs. only 0.4% for placebo over 48 weeks, with all treatment arms meeting the primary endpoint, mean percent change in body weight from the average baseline of 240.5 lbs. (109.1 kg).
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Wegovy and Zepbound autoinjectors

Lilly, Novo MFN deals expected to ‘democratize’ obesity drugs

Nov. 6, 2025
By Mari Serebrov
No Comments
Hailing it as a win-win and a historic step forward in fighting chronic disease, the Trump administration announced pricing agreements Nov. 6 with Eli Lilly and Co. and Novo Nordisk A/S that will expand the availability of the companies’ weight loss drugs by cutting prices and, for the first time, providing coverage for the drugs in obesity through Medicare and Medicaid.
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Deal illustration

CG Bio, Nexgel developing long-acting drug delivery system

Nov. 4, 2025
By Marian (YoonJee) Chu
Nexgel Biotech Co. Ltd. and CG Bio Co. Ltd. agreed to co-develop a thermosensitive polyphosphazene hydrogel-based long-acting drug delivery platform through a new collaboration agreement signed Oct. 31.
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Tape measure wrapped around scale

Wave, Ibio activin E action in obesity early but solid

Oct. 31, 2025
By Randy Osborne
No Comments
The activin E mechanism of action in obesity is having something of an early stage heyday with such players as Wave Life Sciences Ltd. and Ibio Inc. talking up data that have perked the ears of Wall Street.
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Three red darts on target

Novo Nordisk makes $9B counterbid for obesity specialist Metsera

Oct. 30, 2025
By Nuala Moran
No Comments
Pfizer Inc. is threatening legal action at an attempt by Novo Nordisk A/S to scupper its acquisition of Metsera Inc., with an unsolicited $9 billion offer for the anti-obesity specialist. That trumps Pfizer’s agreed bid made in September, which valued New York-based Metsera at $7.3 billion.
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