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BioWorld - Wednesday, December 17, 2025
Home » Topics » Disease categories and therapies » Respiratory

Respiratory
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Respiratory

Actelion Pharmaceuticals describes new PDGFR inhibitors for PAH

Jan. 15, 2024
Actelion Pharmaceuticals Ltd. has identified PDGFR inhibitors reported to be useful for the treatment of pulmonary arterial hypertension (PAH).
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IRG respiratory disease management system
Patents

Immersive Reality details respiratory disease management system

Jan. 12, 2024
By Simon Kerton
In what represents the first patenting from Immersive Reality Group LLC, the company’s co-founders describe their Intellighealth system for detecting the early onset of respiratory diseases using artificial intelligence and wearable remote health monitoring technologies.
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Biomarkers

GDF15 is a marker of fibrotic hypersensitivity pneumonitis

Jan. 12, 2024
Hypersensitivity pneumonitis (HP) is an immune-driven interstitial lung disease occurring when susceptible individuals are exposed to antigens.
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Lumitex
Patents

Lumitex Inc. develops device for acute respiratory distress syndrome

Jan. 10, 2024
By Simon Kerton
Lumitex Inc. seeks patent protection for a phototherapeutic apparatus for treating inflammatory conditions, with a particular focus on treating acute respiratory distress syndrome.
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US prices of asthma, COPD inhalers under HELP microscope

Jan. 9, 2024
By Mari Serebrov
When life-saving inhalers sell in Europe at 1.5% to about 8% of their list price in the U.S., they’re bound to attract scrutiny, especially in a time when inequities in prescription drug prices are fueling more and more legislation to reduce U.S. prices.
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GSK House London

TSLP approach draws GSK to Aiolos buyout: $1B up front

Jan. 9, 2024
By Randy Osborne
GSK plc is plunking down $1 billion cash to take over Aiolos Bio Inc., with the promise of as much as $400 million in regulatory milestone payments along with tiered royalties. The deal gives London-based GSK asthma candidate AIO-001, a phase II-ready, long-acting antibody that binds to the human thymic stromal lymphopoietin (TSLP) ligand to inhibit TSLP signaling and relieve inflammation. GSK said AIO-001 could redefine the standard of care in asthma via the prospect of dosing every six months.
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Biomarkers

Cathepsin Z is hypermethylated in pulmonary arterial hypertension

Jan. 9, 2024
Pulmonary arterial hypertension (PAH), characterized by vasoconstriction and pulmonary vascular remodeling, has a 10% annual mortality rate among patients due to right heart failure. There are genetic variants known to impact the risk of PAH, but susceptibility from epigenetic changes is poorly understood.
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Respiratory

Humanwell Healthcare patents new PDE4 inhibitors

Jan. 5, 2024
Humanwell Healthcare (Group) Co. Ltd. has disclosed compounds acting as phosphodiesterase PDE4 inhibitors, particularly PDE4B, reported to be useful for the treatment of respiratory, gastrointestinal, inflammatory, dermatological, ophthalmic and neurological disorders, transplant rejection and cancer.
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3D illustration of a chain of amino acid or biomolecules called protein
Immune

Kymera Therapeutics unveils first-in-class oral degrader immunology programs

Jan. 5, 2024
Kymera Therapeutics Inc. has unveiled two new first-in-class oral degrader programs for immune-mediated diseases: KT-621, a STAT6 degrader, and KT-294, a TYK2 degrader.
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Respiratory

Roche describes NLRP3 inflammasome inhibitors

Dec. 28, 2023
F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. have patented new NLRP3 inflammasome inhibitors reported to be useful for the treatment of asthma, chronic obstructive pulmonary disease, Parkinson’s and Alzheimer’s diseases.
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